Results 261 to 270 of about 3,197,012 (359)

Comparing Within- and Between-Family Polygenic Score Prediction

bioRxiv, 2019
Saskia Selzam, Stuart J. Ritchie, J. Pingault, C. Reynolds, P. O’Reilly, R. Plomin   +5 more
semanticscholar   +1 more source

Exploring the intersection of polygenic risk scores and prenatal alcohol exposure: Unraveling the mental health equation [PDF]

Lazer Gerlikhman, Dipak K. Sarkar
openalex   +1 more source

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai, Noriki Kutsumura, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source

The Spanish Polygenic Score reference distribution: a resource for personalized medicine. [PDF]

Eur J Hum Genet
Carmona R, Roldán G, Fernández-Rueda JL, Navarro A, Peña-Chilet M, CSVS Crowdsourcing Group, Dopazo J, López-López D.   +7 more
europepmc   +1 more source

Polygenic Risk Scores in Familial Hypercholesterolemia

Journal of the American College of Cardiology, 2019
Daniel J, Rader, Samip, Sheth
openaire   +2 more sources

A century of theories of balancing selection

Biological Reviews, EarlyView.
ABSTRACT Traits that affect organismal fitness are often highly genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature – after all – ‘selects’ the best genotypes at the expense of those that fall short.
Filip Ruzicka, Martyna K. Zwoinska, Debora Goedert, Hanna Kokko, Xiang‐Yi Li Richter, Iain R. Moodie, Sofie Nilén, Colin Olito, Erik I. Svensson, Peter Czuppon, Tim Connallon   +10 more
wiley   +1 more source

Systematic Review and Meta-Analysis: Phenotypic Correlates of the Autism Polygenic Score. [PDF]

JAACAP Open
de Wit MM, Morgan MJ, Libedinsky I, Austerberry C, Begeer S, Abdellaoui A, Ronald A, Polderman TJC.   +7 more
europepmc   +1 more source

Unraveling the Genetic Mysteries of Müllerian Anomalies: Research Approaches and Clinical Significance

Clinical Genetics, EarlyView.
This review primarily summarizes the genetic defects in Müllerian anomalies, the tools used to validate these genetic defects, and the future clinical significance of identifying the precise genetic etiology of Müllerian anomalies. ABSTRACT Müllerian anomalies are a collection of heterogeneous anatomical disorders of the female genital tract that ...
Jingfang Li, Xin Hou, Xiangyu Wang, Juan Li, Li Li, Xiangyi Ma   +5 more
wiley   +1 more source

Rare-Variant Genome-Wide Association and Polygenic Score Assessment of Vitamin D Status in a Middle Eastern Population. [PDF]

Int J Mol Sci
Hendi NN, Umlai UK, Albagha O, Nemer G.
europepmc   +1 more source

Meta Polygenic Risk Score and Lung Cancer Risk Prediction: Two Prospective Cohort Studies

Zhimin Ma, Zhaopeng Zhu, Guanlian Pang, Jiaxin Gao, Wenjing Ge, Guoqing Wang, Mingxuan Zhu, Linnan Gong, Qiao Li, Ji Chen, Yating Fu, Chen Jin, Hongxia Ma, Meng Zhu, Hongbing Shen   +14 more
openalex   +1 more source