Results 261 to 270 of about 2,929,620 (353)

Polygenic Score for the Prediction of Postoperative Nausea and Vomiting: A Retrospective Derivation and Validation Cohort Study. [PDF]

Anesthesiology
Douville NJ, Bastarache L, Bastarache L, He J, Wu KH, Vanderwerff B, Bertucci-Richter E, Hornsby WE, Lewis A, Jewell ES, Kheterpal S, Shah N, Mathis M, Engoren MC, Douville CB, Surakka I, Willer C, Kertai MD.   +17 more
europepmc   +1 more source

Polygenic Risk Scores: What Are They Good For? [PDF]

Biological Psychiatry, 2018
Amanda B Zheutlin, David A. Ross
openaire   +2 more sources

A Type 1 Diabetes Polygenic Score Is Not Associated With Prevalent Type 2 Diabetes in Large Population Studies. [PDF]

J Endocr Soc, 2023
Srinivasan S, Wu P, Mercader JM, Udler MS, Porneala BC, Bartz TM, Floyd JS, Sitlani C, Guo X, Haessler J, Kooperberg C, Liu J, Ahmad S, van Duijn C, Liu CT, Goodarzi MO, Florez JC, Meigs JB, Rotter JI, Rich SS, Dupuis J, Leong A.   +21 more
europepmc   +1 more source

How Intelligence Affects Fertility 30 Years On: Retherford and Sewell Revisited — With Polygenic Scores and Numbers of Grandchildren [PDF]

, 2019
Michael A. Woodley of Menie, Heiner Rindermann, Jonatan Pallesen, Matthew A. Sarraf   +3 more
openalex   +1 more source

Cardiovascular Risk Predicts White Matter Hyperintensities, Brain Atrophy and Treatment Resistance in Major Depressive Disorder: Role of Genetic Liability

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Depressive disorders are a leading cause of global disease burden, particularly with the challenge of treatment‐resistant depression (TRD). Research points to a complex bidirectional relationship between cardiovascular (CV) risk factors and TRD, with CV risk negatively impacting brain structure and potentially influencing ...
Marco Paolini, Melania Maccario, Virginia Saredi, Anna Verri, Federico Calesella, Laura Raffaelli, Cristina Lorenzi, Sara Spadini, Raffaella Zanardi, Cristina Colombo, Sara Poletti, Francesco Benedetti   +11 more
wiley   +1 more source

The interplay between externalizing disorders polygenic risk scores and contextual factors on the development of marijuana use disorders

, 2018
Jill A. Rabinowitz, Rashelle J. Musci, Adam J. Milam, Kelly S. Benke, George R. Uhl, Danielle Y. Sisto, Nicholas S. Ialongo, Brion S. Maher   +7 more
openalex   +2 more sources

Polygenic risk scores in psychiatry: Will they be useful for clinicians? [PDF]

, 2019
Janice M. Fullerton, John I. Nürnberger
openalex   +1 more source

Development of a polygenic score predicting drug resistance and patient outcome in breast cancer. [PDF]

NPJ Precis Oncol
Sahu D, Shi J, Segura Rueda IA, Chatrath A, Dutta A.   +4 more
europepmc   +1 more source

Improved genetic prediction of the risk of knee osteoarthritis using the risk factor-based polygenic score. [PDF]

Arthritis Res Ther, 2023
Morita Y, Kamatani Y, Ito H, Ikegawa S, Kawaguchi T, Kawaguchi S, Takahashi M, Terao C, Ito S, Nishitani K, Nakamura S, Kuriyama S, Tabara Y, Matsuda F, Matsuda S, Nagahama study group.   +15 more
europepmc   +1 more source

Disentangling the effects of nicotine versus non‐nicotine constituents of tobacco smoke on major depressive disorder: A multivariable Mendelian randomisation study

Addiction, EarlyView.
Abstract Background and aims There is growing evidence that tobacco smoking causes depression, but it is unclear which constituents of tobacco smoke (e.g. nicotine, carbon monoxide) may be responsible. We used Mendelian randomisation (MR) to measure the independent effect of nicotine on depression, by adjusting the effect of circulating nicotine ...
Chloe Burke, Gemma Taylor, Tom P. Freeman, Hannah Sallis, Robyn E. Wootton, Marcus R. Munafò, Christina Dardani, Jasmine Khouja   +7 more
wiley   +1 more source