Results 271 to 280 of about 2,929,620 (353)

Shared Genetic Links Between Sleep, Neurodevelopmental and Neuropsychiatric Conditions: A Genome-Wide and Pathway-Based Polygenic Score Analysis. [PDF]

Genes Brain Behav
Fahey L, Lopez LM.
europepmc   +1 more source

Improved Genomic Prediction of Staphylococcus epidermidis Isolation Sources with a Novel Polygenic Score. [PDF]

J Clin Microbiol, 2023
Hellmann KT, Challagundla L, Gray BM, Robinson DA.   +3 more
europepmc   +1 more source

Methods for multiancestry genome‐wide association study meta‐analysis

Annals of Human Genetics, EarlyView.
Abstract Genome‐wide association studies (GWAS) have significantly enhanced our understanding of the genetic basis of complex diseases. Despite the technological advancements, gaps in our understanding remain, partly due to small effect sizes and inadequate coverage of genetic variation.
Chuan Fu Yap, Andrew P. Morris
wiley   +1 more source

Multi-polygenic score prediction of mathematics, reading, and language abilities independent of general cognitive ability. [PDF]

Mol Psychiatry
Procopio F, Liao W, Rimfeld K, Malanchini M, von Stumm S, Allegrini AG, Plomin R.   +6 more
europepmc   +2 more sources

Gene set enrichment analysis to create polygenic scores: a developmental examination of aggression [PDF]

, 2019
Kit K. Elam, Sierra Clifford, Daniel S. Shaw, Melvin N. Wilson, Kathryn Lemery‐Chalfant   +4 more
openalex   +1 more source

Incorporating familial risk, lifestyle factors, and pharmacogenomic insights into personalized noncommunicable disease (NCD) reports for healthcare funder beneficiaries participating in the Open Genome Project

Annals of Human Genetics, EarlyView.
Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk, Nicole Van Der Merwe, Johny Erasmus, Lindiwe Whati, Kelebogile E. Moremi, Daniel W. Olivier, Maritha J. Kotze   +6 more
wiley   +1 more source

Predictive power of the ADHD GWAS 2019 polygenic risk scores in independent samples of bipolar patients with childhood ADHD [PDF]

, 2019
Maria Grigoroiu‐Serbânescu, Giovanni Giaroli, Johan H. Thygesen, Oris Shenyan, Tim B. Bigdeli, Nicholas Bass, Carmen C. Diaconu, Ana Iulia Neagu, Andreas J. Forstner, Franziska Degenhardt, Stefan Herms, Markus M. Nöthen, Andrew McQuillin   +12 more
openalex   +1 more source

Genetic Determinants of the Familial Hypercholesterolaemia Phenotype

Annals of Human Genetics, EarlyView.
ABSTRACT Individuals with familial hypercholesterolaemia (FH) have severely elevated plasma concentrations of low‐density lipoprotein cholesterol (LDL‐C) from birth and as a consequence have an elevated morbidity and mortality due to the development of coronary heart disease (CHD).
Steve Eric Humphries, Marta Futema
wiley   +1 more source

Common (Genetic) Links Between Clinics and the Community: New Evidence From a Tourette Syndrome Polygenic Score [PDF]

, 2019
Angelica Ronald
openalex   +1 more source

Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction. [PDF]

Breast Cancer Res
Yiangou K, Mavaddat N, Dennis J, Zanti M, Wang Q, Bolla MK, Abubakar M, Ahearn TU, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Augustinsson A, Baten A, Behrens S, Bermisheva M, de Gonzalez AB, Białkowska K, Boddicker N, Bodelon C, Bogdanova NV, Bojesen SE, Brantley KD, Brauch H, Brenner H, Camp NJ, Canzian F, Castelao JE, Cessna MH, Chang-Claude J, Chenevix-Trench G, Chung WK, NBCS Collaborators, Colonna SV, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, Devilee P, Dörk T, Dunning AM, Eccles DM, Eliassen AH, Engel C, Eriksson M, Evans DG, Fasching PA, Fletcher O, Flyger H, Fritschi L, Gago-Dominguez M, Gentry-Maharaj A, González-Neira A, Guénel P, Hahnen E, Haiman CA, Hamann U, Hartikainen JM, Ho V, Hodge J, Hollestelle A, Honisch E, Hooning MJ, Hoppe R, Hopper JL, Howell S, Howell A, ABCTB Investigators, kConFab Investigators, Jakovchevska S, Jakubowska A, Jernström H, Johnson N, Kaaks R, Khusnutdinova EK, Kitahara CM, Koutros S, Kristensen VN, Lacey JV, Lambrechts D, Lejbkowicz F, Lindblom A, Lush M, Mannermaa A, Mavroudis D, Menon U, Murphy RA, Nevanlinna H, Obi N, Offit K, Park-Simon TW, Patel AV, Peng C, Peterlongo P, Pita G, Plaseska-Karanfilska D, Pylkäs K, Radice P, Rashid MU, Rennert G, Roberts E, Rodriguez J, Romero A, Rosenberg EH, Saloustros E, Sandler DP, Sawyer EJ, Schmutzler RK, Scott CG, Shu XO, Southey MC, Stone J, Taylor JA, Teras LR, van de Beek I, Willett W, Winqvist R, Zheng W, Vachon CM, Schmidt MK, Hall P, MacInnis RJ, Milne RL, Pharoah PDP, Simard J, Antoniou AC, Easton DF, Michailidou K.   +129 more
europepmc   +1 more source