Results 301 to 310 of about 3,197,012 (359)

Global Patterns of Comorbidities Among Patients With Hidradenitis Suppurativa: A Systematic Review and Meta‐Analysis

International Journal of Dermatology, EarlyView.
ABSTRACT Background Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder increasingly recognized as a systemic disease with diverse comorbidities. While several comorbid conditions are well documented, regional differences in prevalence remain unclear.
Aditya K. Gupta, Amanda Liddy, Vasiliki Economopoulos, Renata Magalhaes   +3 more
wiley   +1 more source

Genetic loci associated with heart rate variability and their effects on cardiac disease risk [PDF]

, 2017
et al,, Stein, Phyllis K
core   +1 more source

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

The accuracy of polygenic score models for BMI and Type II diabetes in the Native Hawaiian population. [PDF]

Commun Biol
Lo YC, Tian H, Chan TF, Jeon S, Alatorre K, Dinh BL, Maskarinec G, Taparra K, Nakatsuka N, Yu M, Chen CY, Lin YF, Wilkens LR, Le Marchand L, Haiman CA, Chiang CWK.   +15 more
europepmc   +1 more source

Weighing the Genetic Risk: Associations Between Polygenic Risk Scores for Cardiometabolic Phenotypes and Adolescent Depression and Body Dissatisfaction

Krista M. Ekberg, Giorgia Michelini, Kristin L. Schneider, Anna R. Docherty, Andrey A. Shabalin, Greg Perlman, Roman Kotov, Daniel N. Klein, Monika A. Waszczuk   +8 more
openalex   +1 more source

Genetic Determinants of Peanut‐Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study

Immunology, EarlyView.
A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan, Karen Cerosaletti, James A. Perry, George DuToit, Monali Manohar, Hua Ling, Justin E. Paschall, Srinath Sanda, R. Sharon Chinthrajah, Gerald T. Nepom, Kari C. Nadeau, Stacie M. Jones, Gideon Lack, Ingo Ruczinski, Rasika A. Mathias   +14 more
wiley   +1 more source

Polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification. [PDF]

Alzheimers Dement
D'Aoust T, Clocchiatti-Tuozzo S, Rivier CA, Mishra A, Hachiya T, Grenier-Boley B, Soumaré A, Duperron MG, Le Grand Q, Bouteloup V, Proust-Lima C, Samieri C, Neuffer J, Sargurupremraj M, Chêne G, Helmer C, Thibault M, Amouyel P, Lambert JC, Kamatani Y, Jacqmin-Gadda H, Tregouët DA, Inouye M, Dufouil C, Falcone GJ, Debette S.   +25 more
europepmc   +1 more source

Assortative mating on educational attainment leads to genetic spousal resemblance for polygenic scores

, 2016
David Hugh-Jones, Karin J. H. Verweij, Beaté St Pourcain, Abdel Abdellaoui   +3 more
openalex   +2 more sources

Unravelling Twin Births in German Holstein Cows: Phenotypic Associations, Genetic Analysis and Potential Underlying Genes and Hormones

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Twin births in dairy cattle are rare but present significant challenges for animal welfare, as both the health of the cow and the calves are affected. This causes economic losses, which prompts breeders to select against twin births and identify associated risk factors.
Laura Hüneke, Hatem Alkhoder, Dierck Segelke, Georg Thaller, Christin Schmidtmann   +4 more
wiley   +1 more source

The impact of polygenic score and socioeconomic status in predicting risk for 19 complex diseases

Hagenbeek FA, Richmond A, Tamlander M, Detrois K, Yang Z, Hartonen T, McCartney DL, FinnGen, Marioni RE, Martikainen P, Mars N, Ganna A, Ripatti S.   +12 more
europepmc   +1 more source