Results 301 to 310 of about 2,929,620 (353)

Novel signals and polygenic score for height are associated with pubertal growth traits in Southwestern American Indians. [PDF]

Hum Mol Genet
Ramírez-Luzuriaga MJ, Kobes S, Hsueh WC, Baier LJ, Hanson RL.   +4 more
europepmc   +1 more source

What’s UPDOG? A novel tool for trans-ancestral polygenic score prediction

, 2023
Howard DM, Pain O, Gillett AC, Vassos E, Lewis CM.   +4 more
europepmc   +1 more source

Adaptive functioning in children and young adults with monogenic neurodevelopmental disorders

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16264 Abstract Aim To examine the adaptive behaviour profiles of children with monogenic neurodevelopmental disorders (NDDs) to determine whether syndrome‐specific or transdiagnostic approaches provide a better understanding of the adaptive behavioural phenotypes of these NDDs ...
Emma K. Baker, Miya St John, Ruth Braden, Lottie D. Morison, Elana J. Forbes, Fatma Lelik, Stephen J. C. Hearps, David J. Amor, Angela T. Morgan   +8 more
wiley   +1 more source

Polygenic Score for Conscientiousness Is a Protective Factor for Reversion from Mild Cognitive Impairment to Normal Cognition. [PDF]

Adv Sci (Weinh)
Yang X, Wang Z, Li H, Qin W, Liu N, Liu Z, Wang S, Xu J, Wang J, Alzheimer's Disease Neuroimaging Initiative.   +9 more
europepmc   +1 more source

Pathogenic variants in chromatin‐related genes: Linking immune dysregulation to neuroregression and acute neuropsychiatric disorders

Developmental Medicine &Child Neurology, EarlyView.
Chromatin machinery influences how DNA is ‘wrapped’ around histones in the nucleosome of immune and brain cells. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16299 Abstract We report eight children with de novo pathogenic DNA variants in chromatin‐related genes: MORC2, CHD7, KANSL1, KMT2D, ZMYND11, HIST1HIE, EP300, and KMT2B.
Russell C. Dale, Shekeeb Mohammad, Velda X. Han, Hiroya Nishida, Himanshu Goel, Stuart G. Tangye, Georgina Hollway, Esther Tantsis, Deepak Gill, Shrujna Patel, Chromatin Immune‐Brain Group, Michael Lonergan, Melanie Wong, Kavitha Kothur, Erica Tsang   +14 more
wiley   +1 more source

An 8-SNP LDL Cholesterol Polygenic Score: Associations with Cardiovascular Risk Traits, Familial Hypercholesterolemia Phenotype, and Premature Coronary Heart Disease in Central Romania. [PDF]

Int J Mol Sci
Mănescu IB, Gabor MR, Moldovan GV, Hadadi L, Huțanu A, Bănescu C, Dobreanu M.   +6 more
europepmc   +1 more source

Obesity‐related glomerulopathy: How it happens and future perspectives

Diabetic Medicine, EarlyView.
Abstract Obesity‐related glomerulopathy (ORG) is an emerging complication of excess adiposity. Its incidence rises alongside the obesity pandemic. Up to 40% of individuals can be affected by ORG, irrespective of the status of glomerular filtration rate and albuminuria.
Jian‐Wen Samuel Lee‐Boey, Jia‐Kai Tan, Zhan‐Foong Lim, Francesco Zaccardi, Kamlesh Khunti, Majid Ezzati, Edward W. Gregg, Lee‐Ling Lim   +7 more
wiley   +1 more source

Assessing the Structure and Specificity of Polygenic Scores for Psychiatric Disorders in a Population-based Cohort of Older Adults [PDF]

, 2019
Arianna M. Gard, Erin B. Ware, Luke W. Hyde, Lauren Schmitz, Jessica D. Faul, Colter Mitchell   +5 more
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