Results 111 to 120 of about 9,196 (170)

Insights into neurodevelopmental features of Huntington's disease from stem cell-derived models including organoids. [PDF]

J Huntingtons Dis
Sierra M, Powers R, Grotewold N, Paulson H.   +3 more
europepmc   +1 more source

Proteostasis disruption and lipid dyshomeostasis in neurodegeneration: exploring common druggable targets across sporadic and monogenic disorders. [PDF]

Front Mol Neurosci
Pereira Sena P, Friedrich L, Villarreal A, Fath F, Sopco L, Hernández-Guillamon M, Saraiva-Pereira ML, Britton G, Weber JJ, Schmidt T.   +9 more
europepmc   +1 more source

Analysis of short tandem repeats linked to polyglutamine diseases from whole-genome sequencing reveals intermediate alleles of <i>HTT</i> associated with an early disease onset in <i>C9orf72</i> carriers. [PDF]

Brain Commun
Barbier M, Gareau T, Camuzat A, Guillaud-Bataille M, Boluda S, Clot F, Araktingi L, Borroni B, van der Zee J, Ghidoni R, Bellini S, Galimberti D, Rossi G, Nacmias B, De la Casa-Fages B, Pastor P, French Clinical and Genetic Research Network on FTD/FTD-ALS and PrevDemALS Study Groups , Latouche M, le Guern E, Durr A, Laquerrière A, Moccia R, Seilhean D, Alvarez V, Le Ber I.   +24 more
europepmc   +1 more source

Revisiting the clastosome: a stress-induced nuclear proteolytic compartment of mammalian cells. [PDF]

Front Neuroanat
Lafarga M, Berciano MT, Rueda N, Cardona-Cortés S, Tapia O.   +4 more
europepmc   +1 more source

Biomarkers in Spinocerebellar Ataxias. [PDF]

Cerebellum
Klockgether T, Grobe-Einsler M, Faber J.
europepmc   +1 more source

Targeting UCHL3 attenuates pathological markers in neuronal models of Huntington's disease. [PDF]

Brain
Ishtayeh H, Battistoni E, Pochtar S, McHugh TLM, Tshilenge KT, Rossmiller B, Amer-Sarsour F, Berdichevsky Y, Muchtar N, Weil M, Ellerby LM, Ashkenazi A.   +11 more
europepmc   +1 more source

Retrotransposition Events Shape the Evolution of the Ataxin-3 Gene Family in Primates. [PDF]

Genome Biol Evol
Felício D, Martins IM, Pinto A, Sequeiros J, Amorim A, Lopes AM, Seixas S, Martins S.   +7 more
europepmc   +1 more source

Familial spinocerebellar ataxia type 3: A case report of multi-generational presentation. [PDF]

Medicine (Baltimore)
Wang J, Liu Z, Shi C, Pan C, Chen J, Zhao Z, Yang D, Huang H.   +7 more
europepmc   +1 more source

Electrical silencing of dendritic arborization neurons rescues toxic polyglutamine-induced locomotion defect. [PDF]

Fly (Austin)
Miao H, Kim WJ.
europepmc   +1 more source

PROTACs therapeutically target the polyglutamine androgen receptor in spinal and bulbar muscular atrophy models. [PDF]

Neurotherapeutics
Sangotra A, Reddy SL, Kuo CJ, Xiang W, Merry DE, Grunseich C, Wang S, Lieberman AP.   +7 more
europepmc   +1 more source