Results 151 to 160 of about 1,539 (210)

Incorporation of polygodial in Langmuir films of selected lipids

Thin Solid Films, 2019
Abstract Identification of membrane sites capable of drug binding is important to understand the interaction of bioactive compounds with biointerfaces such as microbial cellular membranes. As the exact molecular mechanism of action is yet to be fully understood for many drugs, in this study, polygodial, an antimicrobial compound, was incorporated in ...
Giulia E G Gonçalves   +3 more
semanticscholar   +2 more sources

Polygodial: a contact active antifouling biocide

Biofouling, 2014
Ongoing investigation of the candidate antifouling (AF) biocide polygodial (PG) has revealed that this compound may be contact active, whereby it can confer effect while remaining bound within a stable matrix. To test this hypothesis, the AF activity of PG-laced coatings was compared to that of seawater in which PG-laced coatings had been soaked.
P. Cahill, J.M. Kuhajek
semanticscholar   +3 more sources

Polygodial, an antifungal potentiator.

Journal of Natural Products, 1988
A series of sesquiterpene dialdehydes was isolated from the East African medicinal plants Warburgia stuhlmannii and Warburgia ugandensis (Canellaceae) as antibiotics, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana. Among these sesquiterpene dialdehydes, polygodial [1] exhibited the most potent activity.
I. Kubo, M. Taniguchi
semanticscholar   +3 more sources

Antifungal mechanism of polygodial.

Journal of Agricultural and Food Chemistry, 2001
The primary antifungal action of polygodial comes in part from its ability to function as a nonionic surfactant, disrupting the lipid-protein interface of integral proteins and denaturing their conformation. As a result, the antifungal mechanism of this sesquiterpene dialdehyde is associated with the membrane functions or derangement of the membrane ...
I. Kubo, Ken-Ichi Fujita, S. H. Lee
semanticscholar   +3 more sources

Antibacterial activity of polygodial

Phytotherapy Research, 2005
Polygodial was found to possess moderate antibacterial activity against gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus and gram-negative bacteria including Escherichia coli and Salmonella choleraesuis with minimum bactericidal concentrations (MBC) of 100 and 100 microg/mL (0.34 mm) and 100 and 50 microg/mL, respectively.
I. Kubo   +3 more
semanticscholar   +3 more sources

Sesquiterpene Polygodial from Drimys brasiliensis (Winteraceae) Down-Regulates Implant-Induced Inflammation and Fibrogenesis in Mice.

Journal of Natural Products, 2020
Drimys brasiliensis (Winteraceae) has been investigated in traditional medicine for its anti-inflammatory properties to treat gastric ulcers and allergic and respiratory system diseases as well as for cancer treatment.
B. Ferreira   +7 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy