Supercycloalkanes: dihydropyrazine-embedded macrocycles with flexible conformations resembling cycloalkanes. [PDF]
Qiu S, Zhang L, Qu DH, Wang Z.
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Chemical Profiling of Drimys granadensis (Winteraceae) Essential Oil, and Their Antimicrobial, Antioxidant, and Anticholinesterase Properties. [PDF]
Cartuche L +4 more
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Metabolomic Profiling of <i>Pogostemon cablin</i> Reveals Disruption of Secondary Metabolite Biosynthesis Induced by <i>Corynespora cassiicola</i> Infection. [PDF]
Liao RX +4 more
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Surface Chemistry of Cytosporone-B Incorporated in Models for Microbial Biomembranes as Langmuir Monolayers. [PDF]
Jaroque GN +3 more
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Incorporation of polygodial in Langmuir films of selected lipids
Thin Solid Films, 2019Abstract Identification of membrane sites capable of drug binding is important to understand the interaction of bioactive compounds with biointerfaces such as microbial cellular membranes. As the exact molecular mechanism of action is yet to be fully understood for many drugs, in this study, polygodial, an antimicrobial compound, was incorporated in ...
Giulia E G Gonçalves +3 more
semanticscholar +2 more sources
Polygodial: a contact active antifouling biocide
Biofouling, 2014Ongoing investigation of the candidate antifouling (AF) biocide polygodial (PG) has revealed that this compound may be contact active, whereby it can confer effect while remaining bound within a stable matrix. To test this hypothesis, the AF activity of PG-laced coatings was compared to that of seawater in which PG-laced coatings had been soaked.
P. Cahill, J.M. Kuhajek
semanticscholar +3 more sources
Polygodial, an antifungal potentiator.
Journal of Natural Products, 1988A series of sesquiterpene dialdehydes was isolated from the East African medicinal plants Warburgia stuhlmannii and Warburgia ugandensis (Canellaceae) as antibiotics, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana. Among these sesquiterpene dialdehydes, polygodial [1] exhibited the most potent activity.
I. Kubo, M. Taniguchi
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Antifungal mechanism of polygodial.
Journal of Agricultural and Food Chemistry, 2001The primary antifungal action of polygodial comes in part from its ability to function as a nonionic surfactant, disrupting the lipid-protein interface of integral proteins and denaturing their conformation. As a result, the antifungal mechanism of this sesquiterpene dialdehyde is associated with the membrane functions or derangement of the membrane ...
I. Kubo, Ken-Ichi Fujita, S. H. Lee
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Antibacterial activity of polygodial
Phytotherapy Research, 2005Polygodial was found to possess moderate antibacterial activity against gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus and gram-negative bacteria including Escherichia coli and Salmonella choleraesuis with minimum bactericidal concentrations (MBC) of 100 and 100 microg/mL (0.34 mm) and 100 and 50 microg/mL, respectively.
I. Kubo +3 more
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Drimys brasiliensis (Winteraceae) has been investigated in traditional medicine for its anti-inflammatory properties to treat gastric ulcers and allergic and respiratory system diseases as well as for cancer treatment.
B. Ferreira +7 more
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