Results 1 to 10 of about 97,053 (258)
Advanced Science, EarlyView.This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva +28 more
wiley +1 more source
A survey of computer representations of trees for realistic and efficient rendering [PDF]
, 2006 This paper gives an overview of computer graphics representations of trees commonly used for the rendering of complex scene of vegetation. Looking for the right compromise between realism and efficiency has lead researchers to consider various types of ...
Boudon, Frédéric +2 more
core
Advanced Science, EarlyView.Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park +19 more
wiley +1 more source
Design and implementation of geographic information system with mobile terminal and 5G network
IET Networks, EarlyView., 2022 Abstract Remote insurance mainly completes quotation, insurance application and payment through the PC terminal and mobile terminal, and the premium directly enters the insurance account. This article takes remote insurance as an example. First, it analyses the requirements of the remote insurance and insurance system, and then collects data from the ...
Huijun Xiao, Tangsen Huang, Ensong Jiang
wiley +1 more source
Advanced Science, EarlyView.This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen +17 more
wiley +1 more source
Phase-Modulation Three-Dimensional Display Using Computer Graphics Data and Its Wide Viewing Zone
, 2012 次元物体の複素振幅分布情報のうち，位相情報のみを 抽出して再生する位相情報表示波面再生ディスプレイの A three-dimensional display system is presented that uses phase-only distribution calculated from polygon-based computer graphics (CG) data.
Nozomu Ueda, K. Nitta, O. Matoba
semanticscholar +1 more source
Advanced Science, EarlyView.This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour +14 more
wiley +1 more source
Advanced Science, EarlyView.Super‐resolution microscopy identifies nano‐sized tau aggregates (nano‐aggregates) and reveals distinct transitions in their morphology and phosphorylation profiles across control, Primary Age‐Related Tauopathy, and Alzheimer's disease brains. Morphology and hyperphosphorylation signatures distinguish physiological from pathological forms, with nano ...
Adriana N. Santiago‐Ruiz +5 more
wiley +1 more source
Gap Processing for Adaptive Maximal Poisson-Disk Sampling [PDF]
, 2013 In this paper, we study the generation of maximal Poisson-disk sets with varying radii. First, we present a geometric analysis of gaps in such disk sets.
Wonka, Peter, Yan, Dong-Ming
core
Advanced Science, EarlyView.This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning +18 more
wiley +1 more source