Results 21 to 30 of about 30,911 (144)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan   +15 more
wiley   +1 more source

Artificial Intelligence‐Assisted Workflow for Transmission Electron Microscopy: From Data Analysis Automation to Materials Knowledge Unveiling

open access: yesAdvanced Materials, EarlyView.
AI‐Assisted Workflow for (Scanning) Transmission Electron Microscopy: From Data Analysis Automation to Materials Knowledge Unveiling. Abstract (Scanning) transmission electron microscopy ((S)TEM) has significantly advanced materials science but faces challenges in correlating precise atomic structure information with the functional properties of ...
Marc Botifoll   +19 more
wiley   +1 more source

Theoretical and Empirical Analysis of a Fast Algorithm for Extracting Polygons from Signed Distance Bounds

open access: yesAlgorithms
Recently, there has been renewed interest in signed distance bound representations due to their unique properties for 3D shape modelling. This is especially the case for deep learning-based bounds.
Nenad Markuš, Mirko Sužnjević
doaj   +1 more source

Advanced Mounting Technique for Improved Imaging and Analysis of Embedded Spheroids and Migrating Cells in Light Sheet Fluorescence Microscopy

open access: yesAdvanced Materials Technologies, EarlyView.
A novel sample holder compatible with the Zeiss Lightsheet 7 microscope improves imaging of spheroids embedded in collagen matrices. By enabling dual‐sided illumination, it enhances image quality and quantitative analysis of migrating cells. This method advances 3D light sheet microscopy for studying tumor invasion and therapeutic responses.
Masoumeh Mohamadian Namaqi   +5 more
wiley   +1 more source

A survey of computer representations of trees for realistic and efficient rendering [PDF]

open access: yes, 2006
This paper gives an overview of computer graphics representations of trees commonly used for the rendering of complex scene of vegetation. Looking for the right compromise between realism and efficiency has lead researchers to consider various types of ...
Boudon, Frédéric   +2 more
core  

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

open access: yesAdvanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy   +13 more
wiley   +1 more source

Steering the Shape‐shifting of Bullvalene‐PdII Complexes Through Steric and Geometric Strain

open access: yesAngewandte Chemie, EarlyView.
This study explores the use of bis‐pyridyl substituted bullvalenes as dynamic shape‐shifting ligands within cis‐capped PdII complexes. The ring position of the pyridyl nitrogen is critical, leading to a range of Pd2L2 metallacycles and simple PdL complexes, each with distinctive bullvalene isomer preferences (represented in the figure by A‐D isomer ...
André P. Birvé   +2 more
wiley   +2 more sources

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

open access: yesAdvanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang   +12 more
wiley   +1 more source

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