Results 161 to 170 of about 11,505 (225)

Safety Assessment of Polyaminopropyl Biguanide (Polyhexamethylene Biguanide Hydrochloride) as Used in Cosmetics

International Journal of Toxicology, 2020
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of Polyaminopropyl Biguanide (polyhexamethylene biguanide hydrochloride), which functions as a preservative in cosmetic products. The Panel reviewed relevant data relating to the safety of this ingredient and concluded that Polyaminopropyl Biguanide is safe in cosmetics in the
Wilbur, Johnson, Ivan, Boyer, Jinqiu, Zhu, Wilma F, Bergfeld, Donald V, Belsito, Ronald A, Hill, Curtis D, Klaassen, Daniel C, Liebler, James G, Marks, Ronald C, Shank, Thomas J, Slaga, Paul W, Snyder, Bart, Heldreth   +12 more
openaire   +2 more sources

Treatment of Acanthamoeba Keratitis with Polyhexamethylene Biguanide

Ophthalmology, 1992
Polyhexamethylene biguanide (PHMB) is a polymeric biguanide disinfectant that has not previously been used in the treatment of infection. Six patients with confirmed Acanthamoeba keratitis were treated with PHMB 0.02%. All patients had uncontrolled keratitis refractory to therapy with multiple conventional antiamebic agents.
D F, Larkin, S, Kilvington, J K, Dart
openaire   +2 more sources

Effect of polyhexamethylene biguanide on rat liver

Toxicology Letters, 2018
Polyhexamethylene biguanide (PHMB), an amphiphilic polymeric biocide, increased liver tumor incidence in male and female rats at 1000 and 1500 mg/L in drinking water, but not at 500 mg/L in previous studies. In another study, PHMB administered in diet at 4000 mg/kg was negative for hepatocellular tumors.
Aparajita, Chowdhury, Lora L, Arnold, Zemin, Wang, Karen L, Pennington, Puttappa, Dodmane, Ana Paula, Farragut-Cardoso, James E, Klaunig, Daniel, Cros, Edmond E, Creppy, Samuel M, Cohen   +9 more
openaire   +2 more sources

Carboxymethyl bacterial cellulose electrospun nanofibers loaded with zinc oxide nanoparticles and polyhexamethylene biguanide for wound healing promotion

Journal of Biomaterials Science. Polymer Edition
This study explores the development of a novel wound dressing incorporating bacterial cellulose (BC) produced by Acetobacter xylinum, which was carboxymethylated to enhance its biomedical applicability.
N. Molaee, Shohreh Fahimirad, Ali Ganji, H. Abtahi   +3 more
semanticscholar   +1 more source

Treatment of Nocardia asteroides Keratitis with Polyhexamethylene Biguanide

Ophthalmology, 1997
Polyhexamethylene biguanide (PHMB) is a polymeric biguanide disinfectant that has been used previously in the treatment of Acanthamoeba keratitis. The authors report the first case of Nocardia asteroides keratitis treated successfully with PHMB. Further studies documenting the efficacy of PHMB against N.
J C, Lin, T P, Ward, D A, Belyea, P, McEvoy, K K, Kramer   +4 more
openaire   +2 more sources

Environmental Fate of Polyhexamethylene Biguanide

Bulletin of Environmental Contamination and Toxicology, 2011
Polyhexamethylene biguanide (PHMB) is used as a bacteriocidal agent in a variety of applications from medical devices to pools, but is highly toxic to some aquatic species. The stability of PHMB in various environmental matrices was examined. 80% of PHMB was present in fortified creek samples after 20 days, but bound immediately to soils with the ...
openaire   +2 more sources

Surgical debridement and type 1 collagen extracellular matrix plus polyhexamethylene biguanide for the management of pressure injuries.

Journal of Wound Care
OBJECTIVE Purified collagen matrix containing a broad-spectrum antimicrobial, polyhexamethylene biguanide (PuraPly Antimicrobial (PCMP); Organogenesis Inc., US) has been shown to be an effective adjunct in managing wounds of different aetiologies.
J. E. Melendez, Karla Chavez, Maribel Henao, Cameron DeShazo, Yeabsera Tamire, Jeyantt S Sankaran, Gabriel Arevalo   +6 more
semanticscholar   +1 more source

Nghiên cứu tác dụng của dung dịch chứa Polyhexamethylene Biguanide Hydrochloride (Latex HB®) trong điều trị vết thương nhiễm khuẩn

Tạp chí Y học Thảm hoạ và Bỏng
Mục tiêu: Đánh giá tác dụng của dung dịch chứa Polyhexamethylene biguanide hydrochloride (Latex HB®) trong điều trị vết thương nhiễm khuẩn. Đối tượng và phương pháp nghiên cứu: 24 vết thương (VT) nhiễm khuẩn của 20 bệnh nhân (BN) điều trị nội trú tại ...
Tiến Dưng Nguyễn, Anh Tuấn Chu, Ngọc Diệp Trần   +2 more
semanticscholar   +1 more source

Polyhexamethylene biguanide dressings in wound management

Nursing Standard, 2011
This article describes wound management using polyhexamethylene biguanide dressings in two patients experiencing multiple comorbidities. Wound bed debridement and bioburden management were important factors in achieving positive results in terms of promoting wound healing and reducing infection and malodour.
openaire   +2 more sources

Assessment of Polyhexamethylene Biguanide Hydrochloride-Resistance in Purpureocillium Species and Development PCR-based Detection Method.

Medical Mycology Journal
Purpureocillium lilacinum is an opportunistic pathogenic fungus associated with endophthalmitis and keratitis. Previously, we isolated the strain P. lilacinum IFM 63780, notable for its high resistance to polyhexamethylene biguanide hydrochloride (PHMB),
Takako Yamamoto, Kouichi Hosoya, Sayaka Ban, T. Yaguchi   +3 more
semanticscholar   +1 more source