Cartilage and bone regeneration: how close are we to bedside? [PDF]
The treatment/regeneration of bone and cartilage diseases or defects, whether induced by rheumatism, joint dysplasia, trauma, or surgery presents great challenges that have not been fully solved by the current therapies.
Canadas, Raphael Faustino +4 more
core +1 more source
Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets
The oligodendrocyte lineage and its roles in development, plasticity, and CNS homeostasis have been shown to have the potential to treat neurological diseases. However, the main obstacles to clinical translation, particularly in terms of BBB challenges and precise delivery.
Qiong Xiang +6 more
wiley +1 more source
Natural-origin polymers as carriers and scaffolds for biomolecules and cell delivery in tissue engineering applications [PDF]
The present paper intends to overview a wide range of natural–origin polymers with special focus on proteins and polysaccharides (the systems more inspired on the extracellular matrix) that are being used in research, or might be potentially useful as ...
Malafaya, P. B. +2 more
core +1 more source
Contemporary electronic devices produce significant waste, harming ecosystems. Innovation in design, consumption, materials, and end‐of‐life management is crucial. This review explores advanced materials for sustainable and responsible electronics, highlighting their potential to reduce environmental and health hazards while improving device ...
Rawan Omar +7 more
wiley +1 more source
Effects of 3D-printed polycaprolactone/��-tricalcium phosphate membranes on guided bone regeneration [PDF]
This study was conducted to compare 3D-printed polycaprolactone (PCL) and polycaprolactone/ -tricalcium phosphate (PCL/ -TCP) membranes with a conventional commercial collagen membrane in terms of their abilities to facilitate guided bone regeneration (
Ahn, G. +11 more
core +1 more source
Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah +9 more
wiley +1 more source
Electrospun Thymosin Beta-4 Loaded PLGA/PLA Nanofiber/ Microfiber Hybrid Yarns for Tendon Tissue Engineering Application [PDF]
Microfiber yarns (MY) have been widely employed to construct tendon tissue grafts. However, suboptimal ultrastructure and inappropriate environments for cell interactions limit their clinical application.
Chen, Shaojuan +5 more
core +1 more source
The use of mesenchymal stem cells for cartilage repair and regeneration: a systematic review. [PDF]
BACKGROUND: The management of articular cartilage defects presents many clinical challenges due to its avascular, aneural and alymphatic nature. Bone marrow stimulation techniques, such as microfracture, are the most frequently used method in clinical ...
A Badri +301 more
core +3 more sources
Integrating Nanotechnology With 3D Printing for Drug Delivery: Bone Regeneration and Beyond
What happens when nanotechnology meets 3D printing? This review explores how their fusion transforms drug delivery and bone regeneration, creating smarter, more adaptable therapies. From nanomaterials to futuristic fabrication methods, the article maps innovations that could redefine personalized medicine and hints at the challenges researchers must ...
Felipe Sousa Siqueira +2 more
wiley +1 more source
This work investigates by the ROP process the chemical structure, thermal, optical and biocompatibility with living cells of the pyrene‐functionalized Py(PCL), Py(PLLA) homopolymers, and Py(PCL‐b‐PLLA) copolymers. It thoroughly confirms their stability, great fluorescence, and capacity to support MCF‐7 cell growth.
Murat Mısır +6 more
wiley +1 more source

