Results 41 to 50 of about 27,252 (197)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

High electrically conductive composites of Polyamide 11 filled with silver nanowires: Nanocomposites processing, mechanical and electrical analysis [PDF]

, 2013
Highly conductive composites of silver nanowires and semicrystalline polyamide 11 for different content were prepared. A newmethod was developed to introduce nanowires: a combination of solventway and an extrusion process.
Caffrey, Ivan, Carponcin, Delphine, Dantras, Eric, Lacabanne, Colette, Lonjon, Antoine   +4 more
core   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Contrôle par percolation dynamique de la conductivité de nanocomposites polymères-nanotubes de carbone [PDF]

, 2014
L'effet de la percolation dynamique sur la conductivité de composites polymères chargés en nanotubes de carbone a été étudié. La réalisation d'étapes de recuits thermiques à l'état fondu a permis de mettre en évidence une augmentation graduelle de ...
Allais, Arnaud, COMBESSIS, Anthony, FLANDIN, Lionel, MAUGIN, Melek   +3 more
core   +1 more source

Accelerated ageing method with chlorine dioxide. Application to additive free polyamide 66 [PDF]

, 2014
With the aim to study the long-term behavior of accessories used in the tap domestic water supply system, the Centre scientifique et technique du bâtiment (CSTB) has developed a tool dedicated to accelerated ageing tests with chlorine dioxide in the ...
COLIN, Xavier, CORREC, Olivier, DAUSEINS, J, EL MAZRY, Chaker, MALLET, J   +4 more
core   +3 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Highly efficient multilayer organic pure-blue-light emitting diodes with substituted carbazoles compounds in the emitting layer [PDF]

, 2006
Bright blue organic light-emitting diodes (OLEDs) based on 1,4,5,8,N-pentamethylcarbazole (PMC) and on dimer of N-ethylcarbazole (N,N'-diethyl-3,3'-bicarbazyl) (DEC) as emitting layers or as dopants in a 4,4'-bis(2,2'-diphenylvinyl)-1,1'-biphenyl (DPVBi)
A Fischer, A Siove, B Geffroy, C Denis, D Adès, M-C Castex, P Maisse, S Chénais, S Forget, Siove A   +9 more
core   +4 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

ETUDE STRUCTURALE ET THERMODYNAMIQUE DE NANOCOMPOSITE SEMI-CRISTALLIN POLYMERE/ARGILE [PDF]

, 2011
Dans ce travail on étudie les effets d’une argile organiquement modifiée sur les propriétés mécaniques et structurales d’un mélange à base de polypropylène (PP) et de caoutchouc naturel (NR) préparé par extrusion à l’état fondu.
Bendjaouahdou, Chaouki
core