Results 41 to 50 of about 504 (149)

A Multi-Omics Analysis Suggests Links Between the Differentiated Surface Metabolome and Epiphytic Microbiota Along the Thallus of a Mediterranean Seaweed Holobiont

open access: yesFrontiers in Microbiology, 2020
Marine macroalgae constitute an important living resource in marine ecosystems and complex ecological interactions occur at their surfaces with microbial communities.
Benoît Paix   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Tailoring Biodegradability of Poly(Butylene Succinate)/Poly(Lactic Acid) Blends With a Deep Eutectic Solvent

open access: yesFrontiers in Materials, 2020
Biodegradable polymers concern an important topic for innovation in materials, as they are supposed to contribute to the reduction in the amount of waste materials, which lead to microplastics with similar properties as conventional polymer materials ...
Emma Delamarche   +6 more
doaj   +1 more source

Technique d’imagerie par rayons X en contraste de phase pour du contrôle de matériaux composite

open access: yese-Journal of Nondestructive Testing, 2023
Le contraste de phase en imagerie par rayons X permet de voir des détails de structures dans les matériaux peu absorbants. Plusieurs techniques existent mais l’interférométrie à décalage multilatérale (IDML) permet une mesure simultanée des gradients de
Laureen Guitard   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Ionic Liquid-Nanostructured Poly(Methyl Methacrylate)

open access: yesNanomaterials, 2019
Here, ionic liquids (ILs) based on imidazolium and ammonium cations were used as modifying agents for poly(methyl methacrylate) (PMMA) by extrusion. The effects of the chemical nature of the cation and/or counter anion on the resulting properties of IL ...
Clarice Fedosse Zornio   +3 more
doaj   +1 more source

Polymerization of Ethylene Glycol Dimethacrylate (EGDM), Using An Algerian Clay as Eco-catalyst (Maghnite-H+ and Maghnite-Na+)

open access: yesBulletin of Chemical Reaction Engineering & Catalysis, 2020
In this paper we have explored a novel and green method to synthesis and polymerize ethylene glycol dimethacrylate (EGDM). This technique consists on using Maghnite (Algerian clay) as a green catalyst to replace toxic catalysts.
Sara Haoue   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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