Results 1 to 10 of about 2,108,892 (310)

Production of positive controls for calcivirus-specific PCR using recombinant baculiovirus technology [PDF]

, 1997
Recent advances in our knowledge of the genetic structure of human caliciviruses (HuCVs) and small round-structured viruses (SRSVs) have led to the development of polymerase chain reaction (PCR)-based molecular tests specific for these viruses.
Butcher, S.A., Gould, E.A.
core  

Structure and Function of Caliciviral RNA Polymerases

Viruses, 2017
Caliciviruses are a leading agent of human and animal gastroenteritis and respiratory tract infections, which are growing concerns in immunocompromised individuals. However, no vaccines or therapeutics are yet available.
Ji-Hye Lee, Mi Sook Chung, Kyung Hyun Kim   +2 more
doaj   +1 more source

Amino acids in the polymerase complex of shorebird-isolated H1N1 influenza virus impact replication and host-virus interactions in mammalian models

Emerging Microbes and Infections
A diverse population of avian influenza A viruses (AIVs) are maintained in wild birds and ducks yet the zoonotic potential of AIVs in these environmental reservoirs and the host-virus interactions involved in mammalian infection are not well understood ...
Yaqin Bai, Hui Lei, Wenjun Song, Sang-Chul Shin, Jiaqi Wang, Biying Xiao, Zeynep A. Koçer, Min-Suk Song, Robert Webster, Richard J. Webby, Sook-San Wong, Mark Zanin   +11 more
doaj   +1 more source

Nuclear RNA Surveillance in \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e: Trf4p-dependent Polyadenylation of Nascent Hypomethylated tRNA and an Aberrant Form of 5S rRNA [PDF]

, 2006
1-Methyladenosine modification at position 58 of tRNA is catalyzed by a two-subunit methyltransferase composed of Trm6p and Trm61p in Saccharomyces cerevisiae.
Anderson, James T., Kadaba, Sujatha A., Wang, Xuying   +2 more
core   +1 more source

Molecular Virology of Hepatitis C Virus (HCV): 2006 Update

International Journal of Medical Sciences, 2006
Fascinating progress in the understanding of the molecular biology of hepatitis C virus (HCV) was achieved recently. The replicon system revolutionized the investigation of HCV RNA replication and facilitated drug discovery.
doaj  

Joint Efforts of Replicative Helicase and SSB Ensure Inherent Replicative Tolerance of G‐Quadruplex

Advanced Science
G‐quadruplex (G4) is a four‐stranded noncanonical DNA structure that has long been recognized as a potential hindrance to DNA replication. However, how replisomes effectively deal with G4s to avoid replication failure is still obscure. Here, using single‐
Lijuan Guo, Yanling Bao, Yilin Zhao, Zhiyun Ren, Lulu Bi, Xia Zhang, Cong Liu, Xi‐Miao Hou, Michelle D. Wang, Bo Sun   +9 more
doaj   +1 more source

LAIV Mutations Selectively Alter Influenza Viral RNA Polymerase Function, Favoring Transcription over Genome Synthesis

Viruses
Influenza viruses cause mild to severe lower respiratory infections, sometimes resulting in hospitalization and death. Vaccination remains the primary prophylactic strategy.
Justin R. Leach, Adrian Oo, Aitor Nogales, Sebastian I. Bosch, Luis Martínez-Sobrido, Changyong Feng, Baek Kim, Stephen Dewhurst   +7 more
doaj   +1 more source

Viral polymerase-host interaction analysis reveals that the association between avian NUP93 and PB1 promotes H5N6 avian influenza virus replication

Microbiology Spectrum
The H5N6 avian influenza virus, a highly pathogenic strain, poses a significant threat to poultry production and public health. The RNA-dependent RNA polymerase (comprising PB1, PB2, and PA proteins) and nucleoprotein of highly pathogenic avian influenza
Lei Cao, Ting Wang, Peilei Ren, Chuxing Cheng, Haiying Mao, Xianfeng Hui, Xian Lin, Xiaotong Hu, Xiaomei Sun, Kun Huang, Meilin Jin   +10 more
doaj   +1 more source

eDNA Replicates, Polymerase and Amplicon Size Impact Inference of Richness Across Habitats

Environmental DNA
Environmental DNA‐based monitoring has been increasingly used in the last decade to monitor biodiversity in aquatic and terrestrial systems. Molecular‐based surveys now allow quick and reliable production of baseline knowledge of species community ...
Jarl Andreas Anmarkrud, Fabricio dosAnjos Santa Rosa, Lisbeth Thorbek, Audun Schrøder‐Nielsen, Silvana Melo Sviggum, Jonathan Stuart Ready, Hugo J. deBoer, Quentin Mauvisseau   +7 more
doaj   +1 more source

Investigation and impact of mammalian adaptation markers on H5N8 high pathogenicity avian influenza polymerase activity. [PDF]

Npj Viruses
Fusade-Boyer M, Kocher A, Bessière P, Figueroa T, Foret-Lucas C, Vergne T, Chevalier C, Ducatez MF, Volmer R.   +8 more
europepmc   +1 more source