Results 101 to 110 of about 2,158,859 (241)

A PB1-K577E Mutation in H9N2 Influenza Virus Increases Polymerase Activity and Pathogenicity in Mice

open access: yesViruses, 2018
H9N2 avian influenza viruses are present in poultry worldwide. These viruses are considered to have pandemic potential, because recent isolates can recognize human-type receptor and several sporadic human infections have been reported.
Haruhiko Kamiki   +6 more
doaj   +1 more source

Induction of Poxvirus Ribonucleic Acid Polymerases [PDF]

open access: bronze, 1968
A. Pitkanen   +3 more
openalex   +1 more source

Balancing Non-Equilibrium Driving with Nucleotide Selectivity at Kinetic Checkpoints in Polymerase Fidelity Control

open access: yesEntropy, 2018
High fidelity gene transcription and replication require kinetic discrimination of nucleotide substrate species by RNA and DNA polymerases under chemical non-equilibrium conditions.
Chunhong Long, Jin Yu
doaj   +1 more source

A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. [PDF]

open access: yes, 2019
Elevated glucose consumption is fundamental to cancer, but selectively targeting this pathway is challenging. We develop a high-throughput assay for measuring glucose consumption and use it to screen non-small-cell lung cancer cell lines against ...
Chen, Bao Ying   +5 more
core   +1 more source

Identification of a New Ribonucleoside Inhibitor of Ebola Virus Replication

open access: yesViruses, 2015
The current outbreak of Ebola virus (EBOV) in West Africa has claimed the lives of more than 15,000 people and highlights an urgent need for therapeutics capable of preventing virus replication.
Olivier Reynard   +5 more
doaj   +1 more source

Polymerase-endonuclease amplification reaction for large-scale enzymatic production of antisense oligonucleotide [PDF]

open access: yes, 2009
Synthetic oligonucleotides are contaminated with highly homologous failure sequences. Oligonucleotide synthesis is difficult to scale up because it requires expensive equipments, hazardous chemicals, and tedious purification process.
Deming Gou, Xiaolong Wang
core   +1 more source

Bioplastics and food packaging: A review

open access: yesCogent Food & Agriculture, 2015
Food packaging as a vital part of the subject of food technology is involved with protection and preservation of all types of foods. Due to economical abundance, petrochemical plastics have been largely used as packaging material due to their desirable ...
Nafisa Jabeen   +2 more
doaj   +1 more source

Multisubunit RNA polymerases

open access: yesCurrent Opinion in Structural Biology, 2002
Transcription of the genetic information in all cells is carried out by multisubunit RNA polymerases (RNAPs). Comparison of the crystal structures of a bacterial and a eukaryotic RNAP reveals a conserved core that comprises the active site and a multifunctional clamp.
openaire   +4 more sources

Home - About - Disclaimer - Privacy