Results 131 to 140 of about 2,616,862 (309)
Changes in the nuclear distribution of DNA polymerase alpha and PCNA/cyclin during the progress of the cell cycle, in a cell-free extract of Xenopus eggs [PDF]
The nuclear distribution of DNA polymerase alpha and PCNA/cyclin in embryonic nuclei has been investigated, in a cell-free extract of Xenopus eggs that recapitulates a basic cell-cycle in vitro, by indirect immunofluorescence microscopy.
Hutchison, C, Kill, IR
core
Influenza A Virus PA Antagonizes Interferon-β by Interacting with Interferon Regulatory Factor 3
The influenza A virus (IAV) can be recognized by retinoic acid-inducible gene I (RIG-I) to activate the type I interferon response and induce antiviral effects.
Chenyang Yi+31 more
doaj +1 more source
DNA coding for bacteriophage T7 RNA polymerase was ligated to a vaccinia virus transcriptional promoter and integrated within the vaccinia virus genome.
T. Fuerst+3 more
semanticscholar +1 more source
A variable neurodegenerative phenotype with polymerase gamma mutation [PDF]
mtDNA replication and repair, causes mitochondrial diseases including autosomal dominant progressive external ophthalmoplegia (PEO),1 childhood hepato-encephalopathy (Alpers– Huttenlocher syndrome), adult-onset spinocerebellar ataxia, and sensory nerve
Baruffini, E.+8 more
core +1 more source
Rabbit haemorrhagic disease virus (RHDV) is a calicivirus that causes acute infections in both domestic and wild European rabbits (Oryctolagus cuniculus). The virus causes significant economic losses in rabbit farming and reduces wild rabbit populations.
Nadya Urakova+5 more
doaj +1 more source
Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I. [PDF]
The mechanism by which DNA polymerases achieve their extraordinary accuracy has been intensely studied because of the linkage between this process and mutagenesis and carcinogenesis. Here, we have used single-molecule fluorescence microscopy to study the
Markiewicz, RP+3 more
core +1 more source
Joint Efforts of Replicative Helicase and SSB Ensure Inherent Replicative Tolerance of G‐Quadruplex
G‐quadruplex (G4) is a four‐stranded noncanonical DNA structure that has long been recognized as a potential hindrance to DNA replication. However, how replisomes effectively deal with G4s to avoid replication failure is still obscure. Here, using single‐
Lijuan Guo+9 more
doaj +1 more source
ANP32B, or not to be, that is the question for influenza virus
The evolutionary history of ANP32 proteins impacts how influenza virus jumps from birds to mammals.
Steven F Baker, Andrew Mehle
doaj +1 more source
The RNA Polymerase II Core Promoter in Drosophila. [PDF]
Transcription by RNA polymerase II initiates at the core promoter, which is sometimes referred to as the "gateway to transcription." Here, we describe the properties of the RNA polymerase II core promoter in Drosophila The core promoter is at a strategic
Kadonaga, James T+2 more
core +1 more source