Error correction during DNA replication
, 2012 DNA polymerase (DNAP) is a dual-purpose enzyme that plays two opposite roles in two different situations during DNA replication. It plays its normal role as a {\it polymerase} catalyzing the elongation of a new DNA molecule by adding a monomer.
Chowdhury, Debashish, Sharma, Ajeet K.
core +1 more source
Profilin and formin constitute a pacemaker system for robust actin filament growth
eLife, 2019 The actin cytoskeleton drives many essential biological processes, from cell morphogenesis to motility. Assembly of functional actin networks requires control over the speed at which actin filaments grow. How this can be achieved at the high and variable
Johanna Funk +8 more
doaj +1 more source
Efficiency of DNA replication in the Polymerase Chain Reactio [PDF]
Proceedings of the National Academy of Sciences Volume 93, Number
23; Pages 12947-12952, November 12, 1996, 2001 We present a detailed kinetic model for the Polymerase Chain Reaction, and model the probability of replication in terms of the physical parameters of the problem. Applying the theory of branching processes, we show the existance of a new phenomenon affecting the probability distribution function of the number of replicants: for small number of initial
arxiv
Deoxyribonucleic Acid-dependent Ribonucleic Acid Polymerase Activity in Cells Infected with Influenza Virus [PDF]
, 1968 R. Borland, Brian W. J. Mahy
openalex +1 more source
A reverse transcriptase ribozyme
eLife, 2017 A highly evolved RNA polymerase ribozyme was found to also be capable of functioning as a reverse transcriptase, an activity that has never been demonstrated before for RNA. This activity is thought to have been crucial for the transition from RNA to DNA
Biswajit Samanta, Gerald F Joyce
doaj +1 more source
Transcriptional Regulation by the Numbers 1: Models [PDF]
arXiv, 2004 The study of gene regulation and expression is often discussed in quantitative terms. In particular, the expression of genes is regularly characterized with respect to how much, how fast, when and where. Whether discussing the level of gene expression in a bacterium or its precise location within a developing embryo, the natural language for these ...
arxiv
Enhanced Deoxyribonucleic Acid Polymerase Activity in Human Embryonic Kidney Cultures Infected with Adenovirus 2 or 12 [PDF]
, 1968 Nada Ledinko
openalex +1 more source
Azotobacter vinelandii RNA polymerase. II - Effect of ribonuclease on polymerase activity [PDF]
Ribonuclease effect on polymerase activity during ribonucleic acid synthesis ...
Krakow, J. S.
core +1 more source
Production of positive controls for calcivirus-specific PCR using recombinant baculiovirus technology [PDF]
, 1997 Recent advances in our knowledge of the genetic structure of human caliciviruses (HuCVs) and small round-structured viruses (SRSVs) have led to the development of polymerase chain reaction (PCR)-based molecular tests specific for these viruses.
Butcher, S.A., Gould, E.A.
core
A Chemical Kinetic Model of Transcriptional Elongation [PDF]
arXiv, 2006 A chemical kinetic model of the elongation dynamics of RNA polymerase along a DNA sequence is introduced. The proposed model governs the discrete movement of the RNA polymerase along a DNA template, with no consideration given to elastic effects. The model's novel concept is a ``look-ahead'' feature, in which nucleotides bind reversibly to the DNA ...
arxiv