Results 161 to 170 of about 1,891,612 (343)

Identification and some properties of a unique DNA polymerase from cells infected with human B-lymphotropic virus.

, 2020
Ashok R. Bapat
openalex   +1 more source

Active transcription and essential role of RNA polymerase II at the centromere during mitosis [PDF]

, 2012
F. Lyn Chan, Owen J. Marshall, Richard Saffery, Bo Won Kim, Elizabeth D. Earle, K. H. Andy Choo, Lee H. Wong   +6 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Process and analytical strategies for the safe production of mRNA vaccines and therapeutics. [PDF]

Mol Biol Rep
Nowak CJA, Liu S, Falconer RJ, Gerstweiler L.   +3 more
europepmc   +1 more source

Regulation of gene transcription by estrogen and progesterone. Lack of hormonal effects on transcription by Escherichia coli RNA polymerase.

, 1980
R D Palmiter, D.C. Lee
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Bidirectional promoters in Escherichia coli: regulatory rules and implications for gene expression noise. [PDF]

Nucleic Acids Res
Warman EA, Forrest D, Stringer AM, Wade JT, Grainger DC.   +4 more
europepmc   +1 more source

Efficient biallelic knock-in in mouse embryonic stem cells by in vivo-linearization of donor and transient inhibition of DNA polymerase θ/DNA-PK

, 2021
Daisuke Arai, Yoichi Nakao
openalex   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Protease-mediated maturation of M-PMV reverse transcriptase into a functional heterodimer. [PDF]

Protein Sci
Kapisheva M, Junková P, Vaněk O, Jalovcová Z, Křížová I, Dostálková A, Rumlová M.   +6 more
europepmc   +1 more source