Results 171 to 180 of about 1,891,612 (343)
Titular: Consejo Superior de Investigaciones Científicas (CSIC)
Blanco Dávila, Luis +2 more
openaire +2 more sources
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Activation of bacterial transcription by distortion of promoter base pairing. [PDF]
Klimova KM +4 more
europepmc +1 more source
S. Tabor, C. Richardson
semanticscholar +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Understanding the Fidelity and Specificity of DNA Polymerase I. [PDF]
Miller BR +7 more
europepmc +1 more source
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin +12 more
wiley +1 more source
Incorporation of arabinose-CTP and arabinose-UTP inhibits viral polymerases by inducing long pauses. [PDF]
Xiao Z +7 more
europepmc +1 more source
Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis
Radhika Malik +8 more
openalex +2 more sources

