Computational analysis of the effect of a binding protein (RbpA) on the dynamics of Mycobacterium tuberculosis RNA polymerase assembly. [PDF]
Bheemireddy S+2 more
europepmc +1 more source
DNA Polymerase Induced by Simian Virus 40
Saul Kit, L Piekarski, D. R. Dubbs
openalex +1 more source
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang+8 more
wiley +1 more source
Dynamic DNA assembly-assisted CRISPR/Cas12a system for lung cancer-associated miRNA analysis. [PDF]
Sheng A+7 more
europepmc +1 more source
Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells
Through a combination of transcriptomic and histone mapping studies integrated with chromatin imaging, we define how chromatin organization in nanoscale packing domains fine tunes the plasticity of cancer stem cells (CSCs) driving evasion from and survival after chemotherapy.
Yinu Wang+20 more
wiley +1 more source
Temporal expression classes and functions of vaccinia virus and mpox (monkeypox) virus genes. [PDF]
Deng Y, Navarro-Forero S, Yang Z.
europepmc +1 more source
An embedded bioprinting enabled‐arrayed patient‐derived organoids (Eba‐PDO) platform that replicates intrinsic and extrinsic tumor characteristics is introduced. Eba‐PDOs more accurately mimic tissue than standard PDOs (Std‐PDOs) due to maturation in the tumor microenvironment.
Jonghyeuk Han+15 more
wiley +1 more source
HPF1 Regulates Pol β Efficiency in Nucleosomes via the Modulation of Total Poly(ADP-Ribose) Synthesis. [PDF]
Kutuzov M+3 more
europepmc +1 more source
Developing Quorum Sensing‐Based Collaborative Dynamic Control System in Halomonas TD01
A standardized and streamlined inducer‐free quorum sensing (QS)‐based collaborative dynamic control pattern is developed for sufficient gene expression control in Halomonas TD by mixing two engineered cells, cells A and B. Proof‐of‐concept studies are designed to test the dynamic control performance in mixed cultures in fed‐batch conditions.
Yi‐Na Lin+12 more
wiley +1 more source
Precise and Accurate DNA-3'/5-Ends Polishing with Thermus thermophilus Phage vb_Tt72 DNA Polymerase. [PDF]
Dorawa S, Kaczorowski T.
europepmc +1 more source