Results 61 to 70 of about 2,158,859 (241)
Polymerase Mu Is a DNA-Directed DNA/RNA Polymerase [PDF]
Molecular and Cellular Biology, 2003 DNA polymerases are defined as such because they use deoxynucleotides instead of ribonucleotides with high specificity. We show here that polymerase mu (pol μ), implicated in the nonhomologous end-joining pathway for repair of DNA double-strand breaks, incorporates both ribonucleotides and deoxynucleotides in a template-directed manner.
Stephanie A. Nick McElhinny +1 more
openaire +3 more sources
Profilin and formin constitute a pacemaker system for robust actin filament growth
eLife, 2019 The actin cytoskeleton drives many essential biological processes, from cell morphogenesis to motility. Assembly of functional actin networks requires control over the speed at which actin filaments grow. How this can be achieved at the high and variable
Johanna Funk +8 more
doaj +1 more source
Translesion synthesis: Y-family polymerases and the polymerase switch
DNA Repair, 2007 Replicative DNA polymerases are blocked at DNA lesions. Synthesis past DNA damage requires the replacement of the replicative polymerase by one of a group of specialised translesion synthesis (TLS) polymerases, most of which belong to the Y-family. Each of these has different substrate specificities for different types of damage.
Lehmann Alan R +7 more
openaire +3 more sources
Accessibility of DNA in Chromatin to DNA Polymerase and RNA Polymerase [PDF]
Proceedings of the National Academy of Sciences, 1973 The accessibility of DNA in chromatin to both exogenous DNA polymerase and RNA polymerase is slight when compared to isolated DNA. DNA in extracted chromatin is somewhat more accessible to these enzymes than is DNA in the chromatin of isolated nuclei; and the DNA template of chromatin is more accessible to DNA polymerase than to RNA polymerase.
Bert Silverman, Alfred E. Mirsky
openaire +3 more sources
A reverse transcriptase ribozyme
eLife, 2017 A highly evolved RNA polymerase ribozyme was found to also be capable of functioning as a reverse transcriptase, an activity that has never been demonstrated before for RNA. This activity is thought to have been crucial for the transition from RNA to DNA
Biswajit Samanta, Gerald F Joyce
doaj +1 more source
Вавиловский журнал генетики и селекции, 2020 Noroviruses (the Caliciviridae family) are a common cause of acute gastroenteritis in all age groups. These small non-envelope viruses with a single-stranded (+)RNA genome are characterized by high genetic variability.
E. V. Zhirakovskaia +5 more
doaj +1 more source
Rescue of Synthetic Genomic RNA Analogs of Rabies Virus by Plasmid-Encoded Proteins [PDF]
, 1994 Proteins eolirely expressed from cDNA wen used to rescue synthetic RNA genome analogs into infectious defective particles or rabies virus (RV). Synthetic negative-stranded RNAs coßtalning 3' · and S'-terminal RV sequences and tnlßscriptional ...
Conzelmann, Karl-Klaus, Schnell, M.-J.
core +3 more sources
Single-peptide DNA-dependent RNA polymerase homologous to multi-subunit RNA polymerase [PDF]
, 2017 Transcription in all living organisms is accomplished by multi-subunit RNA polymerases (msRNAPs). msRNAPs are highly conserved in evolution and invariably share a B400 kDa five-subunit catalytic core.
Forrest, David +3 more
core +2 more sources
eDNA Replicates, Polymerase and Amplicon Size Impact Inference of Richness Across Habitats
Environmental DNAEnvironmental DNA‐based monitoring has been increasingly used in the last decade to monitor biodiversity in aquatic and terrestrial systems. Molecular‐based surveys now allow quick and reliable production of baseline knowledge of species community ...
Jarl Andreas Anmarkrud +7 more
doaj +1 more source
Viruses, 2020 Hepatitis B virus (HBV) polymerase seems to be very hard to express and purify sufficiently, which has long hampered the generation of anti-HBV drugs based on the nature of the polymerase.
Eriko Ohsaki, Keiji Ueda
doaj +1 more source