Results 241 to 250 of about 2,130,838 (296)
Some of the next articles are maybe not open access.
Polymeric micelles for drug delivery
Expert Opinion on Drug Delivery, 2005Polymeric micelles have been the subject of many studies in the field of drug delivery for the past two decades. The interest has specifically been focused on the potential application of polymeric micelles in three major areas in drug delivery: drug solubilisation, controlled drug release and drug targeting.
Hamidreza Montazeri, Aliabadi +1 more
openaire +2 more sources
Colloid Journal, 2010
Polymerized and nonpolymerized micelles of N-acryloyl-11-aminoundecanoic acid and its sodium salt in water and dimethylformamide are studied by viscometry, isothermal diffusion, and dynamic light scattering. It is revealed that the hydrodynamic sizes of polymerized micelles (PMs) obtained via polymerization of the surfactants in aqueous solutions at ...
A. B. Mel’nikov +4 more
openaire +1 more source
Polymerized and nonpolymerized micelles of N-acryloyl-11-aminoundecanoic acid and its sodium salt in water and dimethylformamide are studied by viscometry, isothermal diffusion, and dynamic light scattering. It is revealed that the hydrodynamic sizes of polymerized micelles (PMs) obtained via polymerization of the surfactants in aqueous solutions at ...
A. B. Mel’nikov +4 more
openaire +1 more source
Biomacromolecules, 2019
In the present study, glucose-responsive polymeric complex micelles based on the complexation of phenylboronic-acid-based (PBA-based) block copolymer and diol-functionalized polymers are reported.
Heba Gaballa, P. Théato
semanticscholar +1 more source
In the present study, glucose-responsive polymeric complex micelles based on the complexation of phenylboronic-acid-based (PBA-based) block copolymer and diol-functionalized polymers are reported.
Heba Gaballa, P. Théato
semanticscholar +1 more source
Polymeric micelles in oral chemotherapy
Journal of Controlled Release, 2008Oral administration of anticancer agents is preferred by patients for its convenience and potential for use in outpatient and palliative setting. In addition, oral administration facilitates a prolonged exposure to the cytotoxic agents. Enhancement of bioavailability of emerging cytotoxic agents is a pre-requisite for successful development of oral ...
openaire +2 more sources
Nano Today, 2012
Summary Polymeric micelles provide a platform that can be carefully tuned for drug delivery. The nano-scale aggregates form spontaneously in aqueous solution and can be used to overcome drug insolubility and increase circulation half life. Self-assembled polymeric micelles are dynamic in nature; thermodynamics defines how the system acts as micelles ...
Shawn C. Owen +2 more
openaire +1 more source
Summary Polymeric micelles provide a platform that can be carefully tuned for drug delivery. The nano-scale aggregates form spontaneously in aqueous solution and can be used to overcome drug insolubility and increase circulation half life. Self-assembled polymeric micelles are dynamic in nature; thermodynamics defines how the system acts as micelles ...
Shawn C. Owen +2 more
openaire +1 more source
The Blood Clearance Kinetics and Pathway of Polymeric Micelles in Cancer Drug Delivery.
ACS Nano, 2018Polymer micelles are one of the most investigated nanocarriers for drug delivery; many have entered clinical trials and some are in clinic use, but their delivery systems have not yet shown the expected high therapeutic efficacy in clinics.
Xuanrong Sun +6 more
semanticscholar +1 more source
Polymerization‐Induced Micelle Gelation
Macromolecular Rapid CommunicationsABSTRACT Self‐assembly of polymer micelles offers a novel pathway to supramolecular structures such as 1D nanowires, yet gelation behavior remains underexplored. We demonstrated a universal copolymerization strategy using acrylic acid and methyl methacrylate to fabricate micellar hydrogels. Initiator concentration critically regulates
Liangwei Lu +4 more
openaire +2 more sources
Bioavailability Effect of Methylprednisolone by Polymeric Micelles
Pharmaceutical Research, 2007To investigate the effect of PEO-PPO-PEO polymeric micelles (PM) formulation on the bioavailability of methylprednisolone (MP), a treatment of spinal cord injury (SCI), to the blood and spinal cord (SC) of rabbits.The characteristic of MP formulated with PM (MP/PM) was evaluated by critical micelles concentration (CMC), dynamic light scattering (DLS ...
Ching-Lin, Chen +7 more
openaire +2 more sources
Pharmacokinetics of Polymeric Micelles for Cancer Treatment
Current Drug Metabolism, 2013Polymeric micelles (PMs) have shown promising applications for the drug delivery since they can improve the low water solubility of hydrophobic drugs, reduce toxicity of the drug, protect unstable drugs from degradation or metabolism, and prolong the time of blood circulation.
Chunyan, Wang +2 more
openaire +2 more sources
European journal of pharmaceutics and biopharmaceutics, 2020
We previously developed a nose-to-brain delivery system using poly(ethylene glycol)-polycaprolactone block polymeric micelles modified by a cell-penetrating peptide, Tat (PEG-PCL-Tat).
T. Kanazawa, H. Taki, H. Okada
semanticscholar +1 more source
We previously developed a nose-to-brain delivery system using poly(ethylene glycol)-polycaprolactone block polymeric micelles modified by a cell-penetrating peptide, Tat (PEG-PCL-Tat).
T. Kanazawa, H. Taki, H. Okada
semanticscholar +1 more source