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Development and Evaluation of a Water Soluble Fluorometholone Eye Drop Formulation Employing Polymeric Micelle [PDF]
Pharmaceutics, 2018 Low aqueous solubility of drug causes difficulties in preparation and inconvenience of administration. Polymeric micelles of fluorometholone (FML) using solid dispersion technique were prepared to develop an eye drop formulation with enhanced water ...
Gyubin Noh +8 more
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Polymeric-Micelle-Based Delivery Systems for Nucleic Acids [PDF]
Pharmaceutics, 2023 Nucleic acids can modulate gene expression specifically. They are increasingly being utilized and show huge potential for the prevention or treatment of various diseases.
Genada Sinani +3 more
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Polyion complex micelle formed from tetraphenylethene containing block copolymer
Biomaterials Research, 2017 Background Polymeric micelles attract great attention in drug delivery and therapeutics. Various types of block copolymers have been designed for the application in biomedical fields.
Seong Min Lee, Woo-Dong Jang
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Pharmaceutics, 2019 Icariin (ICA) is a major flavonoid that contains the active compound Epimedii Folium. However, ICA’s pharmacokinetic characteristics remain unsatisfactory due to its low bioavailability, and hence limited drugability.
Lu-Ying Han +4 more
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Development of fluorescent- and radio-traceable T1307-polymeric micelles as biomedical agents for cancer diagnosis: biodistribution on 4T1 tumor-bearing mice [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2022 In recent years, nanocarriers have been studied as promising pharmaceutical tools for controlled drug-delivery, treatment-efficacy follow-up and disease imaging.
Nicole Lecot +7 more
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Polymeric Micelles in Cancer Immunotherapy [PDF]
Molecules, 2021 Cancer immunotherapies have generated some miracles in the clinic by orchestrating our immune system to combat cancer cells. However, the safety and efficacy concerns of the systemic delivery of these immunostimulatory agents has limited their application.
Zhuoya Wan +7 more
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Biomaterials Research, 2022 Background Superparamagnetic iron oxide nanoparticles (SPIO) have been applied for decades to design theranostic polymeric micelles for targeted cancer therapy and diagnostic MR imaging. However, the effects of SPIO on the physicochemical, and biological
Yixin Jiang +5 more
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Acid-Responsive Adamantane-Cored Amphiphilic Block Polymers as Platforms for Drug Delivery
Nanomaterials, 2021 Four-arm star-shaped (denoted as ‘S’) polymer adamantane-[poly(lactic-co-glycolic acid)-b-poly(N,N’-diethylaminoethyl methacrylate) poly(ethylene glycol) monomethyl ether]4 (S-PLGA-D-P) and its linear (denoted as ‘L’) counterpart (L-PLGA-D-P) were ...
Weiqiu Wen, Chong Guo, Jianwei Guo
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Ars Pharmaceutica, 2020 Background: topical antiseptic agents have been used widely in normal skin and wound which is associated with side effects such as systemic toxicity. Objective: Iodine is a non-metallic agent with an antimicrobial property that is used in the clinic as ...
Behzad Sharif Makhmal Zadeh +1 more
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Drug Delivery, 2020 A delivery system based on l-carnitine (LC) conjugated chitosan (CS)-stearic acid polymeric micelles has been developed for improving the oral bioavailability of paclitaxel (PTX) through targeting intestinal organic cation/carnitine transporter 2 (OCTN2).
Tan Yang +6 more
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