Development and Evaluation of a Water Soluble Fluorometholone Eye Drop Formulation Employing Polymeric Micelle [PDF]
Pharmaceutics, 2018 Low aqueous solubility of drug causes difficulties in preparation and inconvenience of administration. Polymeric micelles of fluorometholone (FML) using solid dispersion technique were prepared to develop an eye drop formulation with enhanced water ...
Byoungduck Park, Young Wook Choi
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Synthesis and evaluation of polymeric micelle containing piperacillin/tazobactam for enhanced antibacterial activity [PDF]
Drug Delivery, 2019 Infections caused by multidrug-resistant bacteria such as P. aeruginosa are important therapeutic complications. Piperacillin/Tazobactam is considered a safe antimicrobial agent.
Milani Morteza +4 more
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Polymeric-Micelle-Based Delivery Systems for Nucleic Acids [PDF]
Pharmaceutics, 2023 Nucleic acids can modulate gene expression specifically. They are increasingly being utilized and show huge potential for the prevention or treatment of various diseases.
Meltem Ezgi Durgun +2 more
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Polymeric Micelle of A3B-Type Lactosome as a Vehicle for Targeting Meningeal Dissemination [PDF]
Nanomaterials, 2018 Polymeric micelle of the A3B-type lactosome comprising (poly(sarcosine))3-b-poly(l-lactic acid) was labeled with 111In. The 111In-labeled A3B-type lactosome was administered to the model mice bearing meningeal dissemination and bone metastasis at ...
Kensuke Kurihara +5 more
doaj +4 more sources
Advancing Small-Molecule Immunotherapy Through Polymeric Micelle Delivery [PDF]
PharmaceuticsSmall-molecule immunomodulators have become important components of modern immunotherapy by targeting immune checkpoints, cytokine signaling pathways, metabolic enzymes, and intracellular kinases.
Kiran Suwal +5 more
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Self-assembled polymeric micelle as a novel mRNA delivery carrier [PDF]
Journal of Controlled Release, 2021 Jin Ren, Shengqi Wang, Yiming Cao
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A Systematic, Knowledge Space-Based Proposal on Quality by Design-Driven Polymeric Micelle Development [PDF]
Pharmaceutics, 2021 Ildikó Csóka +2 more
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A Dual-Drug Nanocarrier Strategy for Ocular Fungal Infections: Micelles Embedded in Electrospun Nanofibers [PDF]
MoleculesOcular fungal diseases are associated with severe infection and pain and, in advanced stages, can lead to vision loss. Current treatment options are limited to the topical application of conventional drugs, and the bioavailability of these drugs is quite
Egemen Uzel +5 more
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Development of fluorescent- and radio-traceable T1307-polymeric micelles as biomedical agents for cancer diagnosis: biodistribution on 4T1 tumor-bearing mice [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2022 In recent years, nanocarriers have been studied as promising pharmaceutical tools for controlled drug-delivery, treatment-efficacy follow-up and disease imaging.
Nicole Lecot +7 more
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Biomaterials Research, 2022 Background Superparamagnetic iron oxide nanoparticles (SPIO) have been applied for decades to design theranostic polymeric micelles for targeted cancer therapy and diagnostic MR imaging. However, the effects of SPIO on the physicochemical, and biological
Yixin Jiang +5 more
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