Polymeric Micelle Systems for Oral Drug Delivery of Small Molecule Therapeutics
PharmaceuticsOral administration remains the most convenient and favored route for systemic delivery of small-molecule drugs, primarily due to patient compliance and the absence of invasive procedures. Yet, poor aqueous solubility, chemical/enzymatic instability, and
Eungyeop Lee +6 more
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Polyion complex micelle formed from tetraphenylethene containing block copolymer
Biomaterials Research, 2017 Background Polymeric micelles attract great attention in drug delivery and therapeutics. Various types of block copolymers have been designed for the application in biomedical fields.
Seong Min Lee, Woo-Dong Jang
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International Journal of Nanomedicine, 2016 Tian Zhou,1 Qinglei Dong,1 Yang Shen,2 Wei Wu,1 Haide Wu,1 Xianglin Luo,3 Xiaoling Liao,4 Guixue Wang1 1Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants,
Zhou T +7 more
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Liposomes encapsulating polymeric chitosan based vesicles - a vesicle in vesicle system for drug delivery [PDF]
, 2000 Drug delivery systems comprising vesicles prepared from one amphiphile encapsulating vesicles prepared from a second amphiphile have not been prepared previously due to a tendency of the bilayer components of the different vesicles to mix during ...
Dufès, Christine +7 more
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Pore-tuning to boost the electrocatalytic activity of polymeric micelle-templated mesoporous Pd nanoparticles. [PDF]
Chem Sci, 2019 Understanding how mesoporous noble metal architectures affect electrocatalytic performance is very important for the rational design and preparation of high-performance electrocatalysts.
Li C +8 more
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Mucosal Penetrative Polymeric Micelle Formulations for Insulin Delivery to the Respiratory Tract. [PDF]
Int J NanomedicineJi-Hyun Kang,1,2,* Jin-Hyuk Jeong,1,* Yong-Bin Kwon,1 Young-Jin Kim,1 Dae Hwan Shin,1 Yun-Sang Park,3 Soonsil Hyun,1 Dong-Wook Kim,4 Chun-Woong Park1 1College of Pharmacy, Chungbuk National University, Cheongju, 28160, Republic of Korea; 2School ...
Kang JH +8 more
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Cheminformatics-driven discovery of polymeric micelle formulations for poorly soluble drugs. [PDF]
Sci Adv, 2019 Many drug candidates fail therapeutic development because of poor aqueous solubility. We have conceived a computer-aided strategy to enable polymeric micelle-based delivery of poorly soluble drugs. We built models predicting both drug loading efficiency (
Alves VM +9 more
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Sodium cholate-enhanced polymeric micelle system for tumor-targeting delivery of paclitaxel. [PDF]
Int J Nanomedicine, 2017 Xiaomin Zhang,1,2 Yibo Wu,1 Min Zhang,1 Jing Mao,3 Yun Wu,4 Yingxin Zhang,2 Ju Yao,2 Chang Xu,2 Wenli Guo,1 Bo Yu2 1Beijing Key Laboratory of Special Elastomeric Composite Materials, Beijing Institute of Petrochemical Technology, Beijing, 2Push-Kang ...
Zhang X +9 more
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Acid-Responsive Adamantane-Cored Amphiphilic Block Polymers as Platforms for Drug Delivery
Nanomaterials, 2021 Four-arm star-shaped (denoted as ‘S’) polymer adamantane-[poly(lactic-co-glycolic acid)-b-poly(N,N’-diethylaminoethyl methacrylate) poly(ethylene glycol) monomethyl ether]4 (S-PLGA-D-P) and its linear (denoted as ‘L’) counterpart (L-PLGA-D-P) were ...
Weiqiu Wen, Chong Guo, Jianwei Guo
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Ars Pharmaceutica, 2020 Background: topical antiseptic agents have been used widely in normal skin and wound which is associated with side effects such as systemic toxicity. Objective: Iodine is a non-metallic agent with an antimicrobial property that is used in the clinic as ...
Behzad Sharif Makhmal Zadeh +1 more
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