Results 21 to 30 of about 267,439 (289)

Liposomes encapsulating polymeric chitosan based vesicles - a vesicle in vesicle system for drug delivery [PDF]

, 2000
Drug delivery systems comprising vesicles prepared from one amphiphile encapsulating vesicles prepared from a second amphiphile have not been prepared previously due to a tendency of the bilayer components of the different vesicles to mix during ...
Dufès, Christine, Uchegbu, I.F., Tetley, L., McPhail, Donald   +3 more
core   +4 more sources

Polymeric micelle disruption by cosolvents and anionic surfactants

, 2011
Polymeric surfactants are frequently used to solubilise sparingly water soluble additives, often in conjunction with non-polymeric surfactants and cosolvents.
Schweins R, Jangher A, Paul A, Griffiths PC, King SM, Heenan RK, Griffiths, Peter Charles, A. Paul, Schweins, R., R. Schweins, R.K. Heenan, Heenan, R. K., King, S. M., S.M. King, Paul, Alison, P.C. Griffiths, A. Jangher, Jangher, Abdulhakim   +17 more
core   +2 more sources

A Review of Polymeric Micelles and Their Applications

Polymers, 2022
Self-assembly of amphiphilic polymers with hydrophilic and hydrophobic units results in micelles (polymeric nanoparticles), where polymer concentrations are above critical micelle concentrations (CMCs). Recently, micelles with metal nanoparticles (MNPs) have been utilized in many bio-applications because of their excellent biocompatibility ...
Suguna Perumal, Raji Atchudan, Wonmok Lee   +2 more
openaire   +2 more sources

Preparation and optimization of polymeric micelles as an oral drug delivery system for deferoxamine mesylate: in vitro and ex vivo studies

Research in Pharmaceutical Sciences, 2019
Deferoxamine mesylate (DFO) is administered as a slow subcutaneous or intravenous infusion due to its poor oral bioavailability and lack of dose proportionality.
Anayatollah Salimi, Behzad Sharif Makhmal Zadeh, Moloud Kazemi   +2 more
doaj   +1 more source

Intelligent delivery of antitumor drugs mediated by polymeric nanomicelles: a review [PDF]

Química Nova, 2023
Cancer therapy represents a challenge, even with the current scientific developments. Over the years, several studies have shown that the application of antitumor drug nanocarriers is an efficient strategy; however, it requires further improvement ...
Raquel dos Santos Martins, Adriana Pereira Duarte, Fernando Cotinguiba   +2 more
doaj   +1 more source

pH-responsive polymeric micelles self-assembled from amphiphilic copolymer modified with lipid used as doxorubicin delivery carriers [PDF]

Royal Society Open Science, 2018
In the present study, a novel pH-responsive amphiphilic copolymer, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)] conjugated poly(β-amino esters) (DSPE-b-PEG-b-PAE-b-PEG-b-DSPE), was designed and successfully synthesized
Xin Xin Zhou, Long Jin, Rui Qun Qi, Teng Ma   +3 more
doaj   +1 more source

Highlights on polymeric micelles as versatile nanocarriers for drug transporting

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022
Polymeric micelles are nanoscale core-shell structures formed by amphiphilic (block or graft) copolymers, that can self-aggregate in an aqueous medium.
Hussein A. Abdul Hussein, Nidhal K. Maraie   +1 more
doaj   +1 more source

Optimization and Characterization of Sodium Alginate Beads Providing Extended Release for Antidiabetic Drugs

Molecules, 2023
The current research is aimed at investigating the relationship between the formulation components and conditions in the case of a binary drug delivery system, where antidiabetic drugs are co-formulated into polymeric micelles embedded in sodium alginate.
Bence Sipos, Márk Benei, Gábor Katona, Ildikó Csóka   +3 more
doaj   +1 more source

Casein and acryl amide complexation and bio-adhesive polymeric nano micelles influence on vortioxetine dissolution, penetration enhancement and in vivo absorption

Food Hydrocolloids for Health
Vortioxetine (VTX) is a new atypical antidepressant used to treat major depression and other mental disorders. Due to its low water solubility, oral absorption, and fast metabolism, VTX has been commercially manufactured and sold as a hydrobromide.
Samaa Abdullah, Nabil A. Alhakamy, Hatim S. AlKhatib, Rana Abu Huwaij, Hadil Alahdal, Abeer A. Altamimi   +5 more
doaj   +1 more source

Permeability of Ciprofloxacin-Loaded Polymeric Micelles Including Ginsenoside as P-glycoprotein Inhibitor through a Caco-2 Cells Monolayer as an Intestinal Absorption Model

Molecules, 2018
The low oral bioavailability of ciprofloxacin is associated with two distinct challenges: its low aqueous solubility and efflux by p-glycoproteins (P-gp) in the intestinal membrane.
Behzad Sharif Makhmal Zadeh, Golbarg Esfahani, Anayatollah Salimi   +2 more
doaj   +1 more source