Results 21 to 30 of about 250,640 (230)
Pharmaceutics, 2019 Icariin (ICA) is a major flavonoid that contains the active compound Epimedii Folium. However, ICA’s pharmacokinetic characteristics remain unsatisfactory due to its low bioavailability, and hence limited drugability.
Lu-Ying Han +4 more
doaj +1 more source
Drug Delivery, 2020 A delivery system based on l-carnitine (LC) conjugated chitosan (CS)-stearic acid polymeric micelles has been developed for improving the oral bioavailability of paclitaxel (PTX) through targeting intestinal organic cation/carnitine transporter 2 (OCTN2).
Tan Yang +6 more
doaj +1 more source
Research in Pharmaceutical Sciences, 2019 Deferoxamine mesylate (DFO) is administered as a slow subcutaneous or intravenous infusion due to its poor oral bioavailability and lack of dose proportionality.
Anayatollah Salimi +2 more
doaj +1 more source
Intelligent delivery of antitumor drugs mediated by polymeric nanomicelles: a review [PDF]
Química Nova, 2023 Cancer therapy represents a challenge, even with the current scientific developments. Over the years, several studies have shown that the application of antitumor drug nanocarriers is an efficient strategy; however, it requires further improvement ...
Raquel dos Santos Martins +2 more
doaj +1 more source
pH-responsive polymeric micelles self-assembled from amphiphilic copolymer modified with lipid used as doxorubicin delivery carriers [PDF]
Royal Society Open Science, 2018 In the present study, a novel pH-responsive amphiphilic copolymer, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)] conjugated poly(β-amino esters) (DSPE-b-PEG-b-PAE-b-PEG-b-DSPE), was designed and successfully synthesized
Xin Xin Zhou +3 more
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Toxicity and immunogenicity concerns related to PEGylated-micelle carrier systems: a review
Science and Technology of Advanced Materials, 2019 Polymeric-micelle carrier systems have emerged as a novel drug-carrier system and have been actively studied for anticancer drug targeting. In contrast, toxicological and immunological concerns related to not only polymeric-micelle carrier systems, but ...
Kouichi Shiraishi, Masayuki Yokoyama
doaj +1 more source
Highlights on polymeric micelles as versatile nanocarriers for drug transporting
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022 Polymeric micelles are nanoscale core-shell structures formed by amphiphilic (block or graft) copolymers, that can self-aggregate in an aqueous medium.
Hussein A. Abdul Hussein +1 more
doaj +1 more source
Molecules, 2023 The current research is aimed at investigating the relationship between the formulation components and conditions in the case of a binary drug delivery system, where antidiabetic drugs are co-formulated into polymeric micelles embedded in sodium alginate.
Bence Sipos +3 more
doaj +1 more source
Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia [PDF]
, 2012 This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic® block copolymers, by a new microfluidic approach.
Carugo, D +17 more
core +1 more source
, 2021 Tumor microenvironment (TME) responsive polymeric micelles are promising carriers for drug delivery. In order to meet the needs of various applications, multifarious TME-responsive switches are used to construct smart polymeric micelles, which causes the
Nanxia Zhang (11377866) +17 more
core +1 more source