Results 41 to 50 of about 91,683 (252)

Nonthermal Plasma Technology as a Versatile Strategy for Polymeric Biomaterials Surface Modification: A Review [PDF]

, 2009
In modern technology, there is a constant need to solve very complex problems and to fine-tune existing solutions. This is definitely the case in modern medicine with emerging fields such as regenerative medicine and tissue engineering.
De Geyter, Nathalie, Desmet, Tim, Dubruel, Peter, Leys, Christophe, Morent, Rino, Schacht, Etienne   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Growing Polymer Vesicles Generated by Polymerization Induced Self-Assembly Coupled With a Living Chemical Reactor

Frontiers in Bioengineering and Biotechnology, 2020
Chemical oscillatory reactions have attracted intensive attention due to their autonomous, continuous, and periodic features. Herein, the radicals generated in Belousov-Zhabotinsky (BZ) oscillator was used to initiate RAFT (reversible addition ...
Zhihui Lu, Jinshan Guo
doaj   +1 more source

A pharmacological cocktail for arresting actin dynamics in living cells. [PDF]

, 2011
The actin cytoskeleton is regulated by factors that influence polymer assembly, disassembly, and network rearrangement. Drugs that inhibit these events have been used to test the role of actin dynamics in a wide range of cellular processes.
Peng, Grace E, Weiner, Orion D, Wilson, Sarah R   +2 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Recent progress in polymerization‐induced self‐assembly: From the perspective of driving forces

Aggregate
Polymerization‐induced self‐assembly (PISA) enables the simultaneous growth and self‐assembly of block copolymers in one pot and therefore has developed into a high‐efficiency platform for the preparation of polymer assemblies with high concentration and
Zizhuo Zhao, Shujing Lei, Min Zeng, Meng Huo   +3 more
doaj   +1 more source

Autoinhibition of the formin Cappuccino in the absence of canonical autoinhibitory domains. [PDF]

, 2012
Formins are a conserved family of proteins known to enhance actin polymerization. Most formins are regulated by an intramolecular interaction. The Drosophila formin, Cappuccino (Capu), was believed to be an exception.
Bor, Batbileg, Phillips, Martin L, Quinlan, Margot E, Vizcarra, Christina L   +3 more
core   +2 more sources

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source

A Novel Fabrication of Single Electron Transistor from Patterned Gold Nanoparticle Array Template-Prepared by Polystyrene Nanospheres

Nanomaterials, 2022
In this paper, polystyrene microspheres were firstly prepared by seeded emulsion polymerization, and the uniform monolayer of polystyrene microspheres was prepared on the substrate by the dipping method.
Jingyue Fang, Xinxing Li, Wenke Xie, Kehui Sun   +3 more
doaj   +1 more source