Results 51 to 60 of about 153,918 (233)

) copolymers via polymerization‐induced thermal self‐assembly [PDF]

, 2023
Self‐assembled polymeric nanoparticles have been of great interest for various biological applications such as drug delivery, catalysis, and biosensing.
Kumar, C. M. Santosh; id_orcid, Akar, Irem, Calum Ferguson, Pearce, Amanda K.; id_orcid, Amanda K. Pearce, Irem Akar, C. M. Santosh Kumar, Rachel K. O'Reilly, Ferguson, Calum, O'Reilly, Rachel K.; id_orcid   +9 more
core   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science
Therapeutic agents usually must reach diseased tissue and then exert biological effects. While numerous targeted and stimuli‐responsive delivery systems have been developed, their therapeutic outcomes have been limited due to the lack of “precision”.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Recent progress in polymerization‐induced self‐assembly: From the perspective of driving forces

Aggregate
Polymerization‐induced self‐assembly (PISA) enables the simultaneous growth and self‐assembly of block copolymers in one pot and therefore has developed into a high‐efficiency platform for the preparation of polymer assemblies with high concentration and
Zizhuo Zhao, Shujing Lei, Min Zeng, Meng Huo   +3 more
doaj   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

Advanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

Polymer-inorganic hybrid nanoparticles via polymerization-induced self-assembly [PDF]

, 2019
Silica nanoparticles are commonly integrated within polymeric matrices to form composite materials, due to their non-toxic nature, chemical resistance and physical properties.
Teo, GH (15933944)
core   +1 more source

Extrusion‐Based Additive Manufacturing of Advanced Ceramics: Strengthening Mechanisms and Process Optimization Review

Advanced Engineering Materials, EarlyView.
This review comprehensively evaluates extrusion‐based additive manufacturing for advanced ceramics, detailing feedstock options and key process parameters. By critically addressing defect mechanisms like porosity and cracking, the work highlights optimization strategies through machine learning and advanced postprocessing.
Meisam Bakhtiari, Mohammad Hadi Sheikh‐Ansari, Avinash Borgaonkar, Mehran Dadkhah, Abdollah Saboori   +4 more
wiley   +1 more source

Methacrylate-based amphiphilic block copolymers in solution and at surfaces : synthesis, characterization and self-assembly [PDF]

, 2008
Part 1. Introduction General concept of polymer self-assembly, synthesis of amphiphilic block copolymers and their application in biotechnology are briefly presented.
Rakhmatullina, Ekaterina
core   +1 more source

Asymmetric Polymerization-Induced Crystallization-Driven Self-Assembly of Helical, Rod-Coil Poly(Aryl Isocyanide) Block Copolymers [PDF]

, 2022
The helical motif is ubiquitous in naturally occurring chemical systems where it confers numerous useful and distinct material properties. Accordingly, a great many synthetic materials have been produced in efforts to mimic biological systems.
Ali, Shahrokhinia, Randall, Scanga, Jake, Borges, Michael, Ross, James, Reuther   +4 more
core   +1 more source