Results 31 to 40 of about 359,785 (265)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Discover MaterialsMetal complexes of hyperbranched polymers have attracted attention as potential catalysts due to their unique, tunable structure. Hyperbranched polyester polybenzoylcarbamate was synthesized by the reaction of second-generation hyperbranched polyester ...
Alina Vagapova +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A vaccine-based nanosystem for initiating innate immunity and improving tumor immunotherapy
Nature Communications, 2020 Immune checkpoint blockade (ICB) immunotherapy efficacy has still limitations. Here, the authors generate a vaccine that integrates CD274 siRNA into the L1 protein of human papillomavirus, which cooperates with ICB by activating innate immunity in breast
Di-Wei Zheng +9 more
doaj +1 more source
Geminate labels programmed by two-tone microdroplets combining structural and fluorescent color
Nature Communications, 2021 Creating an enhanced-security-level label that carries entirely distinct information in different optical states has proven challenging. Here, the authors design geminate labels by programming fluorescent cholesteric liquid crystal microdroplets to ...
Lang Qin +7 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Nature Communications, 2020 Traditional ratiometric temperature monitoring is challenging due to the variation in tissue absorption and scattering of different wavelengths. Here, the authors show improved accuracy by using emission at the same wavelength, but different luminescent ...
Xiaochen Qiu +5 more
doaj +1 more source
Nano-Micro Letters, 2022 The anode-free design is a promising strategy to increase the energy density of aqueous Zn metal batteries (AZMBs). However, the scarcity of Zn-rich cathodes and the rapid loss of limited Zn greatly hinder their commercial applications.
Yixiang Zhang +7 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Antioxidants, 2023 A new type of fibrous mat based on a cellulose derivative—cellulose acetate (CA) or CA and water-soluble polymers (polyvinylpyrrolidone, PVP or poly(vinyl alcohol), PVA)—loaded with the model drug 5-nitro-8-hydroxyquinoline (5N) was fabricated via ...
Mariya Spasova +8 more
doaj +1 more source