Results 41 to 50 of about 359,785 (265)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Enhanced antimicrobial activity, mechanical and dielectric properties of styrene butadiene rubber vulcanizates designed for protection products

Scientific Reports
This study focuses on fabricating and evaluating novel, ecofriendly, green, flexible, antimicrobial Styrene Butadiene Rubber vulcanizates for producing safety products.
Doaa E EL-Nashar, Fahima Helaly, Aman Khalaf, Azza A. Ward, Nehad N. Rozik, Abbas Yehia, Mohamed M. Eissa, Sahar A. M. Hussein, Abdelmohsen M. Soliman   +8 more
doaj   +1 more source

Preparation and Characterization of Semi-IPN Cryogels Based on Polyacrylamide and Poly(N,N-dimethylaminoethyl methacrylate); Functionalization of Carrier with Monochlorotriazinyl-β-cyclodextrin and Release Kinetics of Curcumin

Molecules, 2021
Curcumin (CCM) is a natural hydrophobic polyphenol known for its numerous applications in the food industry as a colorant or jelly stabilizer, and in the pharmaceutical industry due to its anti-inflammatory, antibacterial, antioxidant, anti-cancer, and ...
Ecaterina Stela Dragan, Maria Valentina Dinu, Claudiu Augustin Ghiorghita, Maria Marinela Lazar, Florica Doroftei   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Introducing Porphyrin Units by Random Copolymerization Into NDI-Based Acceptor for All Polymer Solar Cells

Frontiers in Chemistry, 2020
Naphthalene diimide (NDI)-based polymer N2200 is a promising organic polymer acceptor for all-polymer solar cells (all-PSCs), but its inherent shortcomings like poor extinction coefficient and strong aggregation limit further performance optimization of ...
Jinliang Liu, Mengzhen Li, Dong Chen, Bin Huang, Qiannan He, Shanshan Ding, Wenquan Xie, Feiyan Wu, Lie Chen, Yiwang Chen, Yiwang Chen   +10 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A novel naturally superoleophilic coconut oil-based foam with inherent hydrophobic properties for oil and grease sorption

Scientific Reports
Absorption methods using polyurethane foams (PUFs) have recently gained popularity in treating oil spills. However, conventional petroleum-based PUFs lack selectivity and are commonly surface-modified using complicated processes that require toxic and ...
Tomas Ralph B. Tomon, Christine Joy M. Omisol, Blessy Joy M. Aguinid, Karyl Xyrra L. Sabulbero, Arnold C. Alguno, Roberto M. Malaluan, Arnold A. Lubguban   +6 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Insight on the impact of Acacia nilotica leaves extract on the characteristics of natural and synthetic rubber composites

Scientific Reports
The purpose of this study is to assess the extract of Acacia nilotica leaves as a sustainable natural antioxidant for natural rubber (NR) and styrene-butadiene rubber (SBR) composites.
T. A. Zidan, Sayed A. El-Toumy, M. N. Ismail, D. E. El-Nashar, A. I. Khalaf   +4 more
doaj   +1 more source

Optically-controlled bacterial metabolite for cancer therapy

Nature Communications, 2018
Targeting tumors with bacteria as vehicles for metabolite therapy suffers from low efficiency and robustness. Here, the authors combine carbon nitride with nitric oxide generation enzyme-positive E.
Di-Wei Zheng, Ying Chen, Zi-Hao Li, Lu Xu, Chu-Xin Li, Bin Li, Jin-Xuan Fan, Si-Xue Cheng, Xian-Zheng Zhang   +8 more
doaj   +1 more source