Results 61 to 70 of about 1,221,997 (261)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Scientific Reports, 2023 The objective of this study is to enhance the effectiveness of anticorrosive coatings applied to steel pipelines utilized for the transportation of petroleum products.
N. M. Ahmed, M. G. Mohamed
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Value-Added Products Derived from Poly(ethylene terephthalate) Glycolysis
MoleculesAmong polymer wastes, poly(ethylene terephthalate) (PET) is the most important commercial thermoplastic polyester. Less than 30% of total PET production is recycled into new products. Therefore, large amounts of waste PET need to be recycled. We describe
Simona Zahova +3 more
doaj +1 more source
Elongation and fluctuations of semi-flexible polymers in a nematic solvent [PDF]
, 2004 We directly visualize single polymers with persistence lengths ranging from $\ell_p=0.05$ to 16 $\mu$m, dissolved in the nematic phase of rod-like {\it fd} virus.
A. Bensimon +25 more
core +3 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Increased Ag nanoparticles stability through cellulose nanofibrils coatings [PDF]
Memoirs of the Scientific Sections of the Romanian Academy, 2020 The study presents the possibility of covering Ag nanoparticles in solutuon with cellulose with cellulose nanofibrils (CNFs)and oxidized cellulose nanofibrils, termed TEMPO (TCNFs)in order to increase their dispersility and stability over time.
Alina Gabriela Rusu +6 more
doaj
Difunctional polyisobutylene prepared by polymerization of monomer on molecular sieve [PDF]
, 1970 Process yields difunctional isobutylene polymers ranging in molecular weight from 1150 to 3600. These polymers have the potential for copolymerization and cross-linking with other monomers to form elastomeric ...
Midler, J. A., Jr.
core +1 more source
Picosecond Laser Ablation of Polyhydroxyalkanoates (PHAs): Comparative Study of Neat and Blended Material Response [PDF]
, 2019 Polyhydroxyalkanoates (PHAs) have emerged as a promising biodegradable and biocompatible material for scaffold manufacturing in the tissue engineering field and food packaging. Surface modification is usually required to improve cell biocompatibility and/
Basnett, P. +7 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source