Results 201 to 210 of about 3,320,990 (271)

Impact of lifestyle modification practices and pharmacogenetics of <i>ACE I/D</i> gene polymorphism in grade 1 hypertensive patients. [PDF]

open access: yesJ Family Med Prim Care
Rahman F   +6 more
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang   +2 more
wiley   +1 more source

Development and application of a multiple nucleotide polymorphism (MNP)-based molecular identification system for pear cultivars. [PDF]

open access: yesBMC Plant Biol
Yang X   +12 more
europepmc   +1 more source

Room‐Temperature Alane Dehydrogenation for Visible‐Light‐Driven Photocatalytic Hydrogen Supply System

open access: yesAdvanced Science, EarlyView.
In situ formed Al/MOF enables viable visible‐light‐driven photocatalytic dehydrogenation of alane (AlH3) confirming practical application. Results demonstrate that Al nanoparticles prolong lifetime of photogenerated charge carriers via localized surface plasmon resonance induced hot electron injection, while AlH3 chemisorption triggers interfacial ...
Ting‐Ting Li   +11 more
wiley   +1 more source

The NSUN5 gene rs1880948 A>G polymorphism and neuroblastoma risk in Chinese children. [PDF]

open access: yesFront Oncol
Ye Z   +10 more
europepmc   +1 more source

Natural Variations of ZmRLR1 Mediate the Root Lodging Resistance of Maize by Regulating Root Ascorbate and Auxin Homeostasis

open access: yesAdvanced Science, EarlyView.
Root lodging severely limits crop yield and quality. We reveal that ZmRLR1, a plasma membrane b‐type cytochrome, regulates lodging resistance in maize through dual roles: modulating intracellular redox balance and functioning as a novel component of clathrin‐mediated endocytosis to influence auxin homeostasis. Moreover, natural variations in the ZmRLR1
Wenshuai Lv   +7 more
wiley   +1 more source

Polymorphic variants in GABA-A receptor and their association with epilepsy and drug resistance: A North Indian cohort study. [PDF]

open access: yesWorld J Psychiatry
Dabla PK   +7 more
europepmc   +1 more source

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

open access: yesAdvanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng   +20 more
wiley   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

open access: yesAdvanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin   +10 more
wiley   +1 more source

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