Results 231 to 240 of about 3,516,071 (372)

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

The development of ideal insertion and deletion (InDel) markers and initial indel map variation in cucumber using re-sequenced data. [PDF]

BMC Genomics
Yang J, Meng P, Mi H, Wang X, Yang J, Fu S, Gong W, Bao R, Deng W, Wu H, Liu Z, Yang S, Ni J, Liu J, Shi H.   +14 more
europepmc   +1 more source

Controllable Crystalline Phases of Multi‐Cation Oxides

Advanced Science, EarlyView.
This work demonstrates the control of crystal phases in rare‐earth titanates containing multiple rare‐earth elements. By combining atomic‐level structure characterization techniques, the atomic structures are elucidated, and entropy of mixing for each phase is quantitatively estimated.
Takafumi Ogawa, Makoto Tanaka, Naoki Kawashima, Taishi Ito, Kei Nakayama, Takeharu Kato, Satoshi Kitaoka   +6 more
wiley   +1 more source

Rs9839776 Genetic Variant of lncRNA SOX2OT Contributes to Susceptibility of Acute Kidney Injury in Sepsis Patients via Regulating SOX2OT/miR-9-5p Axis. [PDF]

J Inflamm Res
Xu S, Cui M, Wang R.
europepmc   +1 more source

Integrating Dense Genotyping with High‐Throughput Phenotyping Empowers the Genetic Dissection of Berry Quality and Resilience Traits in Grapevine

Advanced Science, EarlyView.
Researchers develop advanced tools to study grapevine traits like berry quality and stress resilience. A 200K SNP array and high‐throughput phenotyping enable the identification of loci linked to berry shape, sugar content, acidity, and cold tolerance. Functional validation of genes such as NAC08 reveals roles in cold tolerance.
Yuyu Zhang, Yongjian Wang, Michael Henke, Pablo Carbonell‐Bejerano, Zemin Wang, Pierre‐François Bert, Yi Wang, Huayang Li, Junhua Kong, Peige Fan, Zhanwu Dai, Zhenchang Liang   +11 more
wiley   +1 more source

The frequency of the ACTN3 polymorphism in Brazil: a systematic review and meta-analysis. [PDF]

BMC Med Genomics
Silvino VO, Ferreira CP, Apaza HM, de Souza-Junior VS, Ribeiro SLG, Almeida SS, Dos Santos MAP.   +6 more
europepmc   +1 more source

The Rise of Chalcohalide Solar Cells: Comprehensive Insights From Materials to Devices

Advanced Science, EarlyView.
This review provides a detailed overview of recent advancements in chalcohalide solar cells, focusing on structure design, material chemistry, synthesis methods, and device optimization. It also highlights future directions for improving device efficiency through innovative device architectures and synthesis techniques, addressing key challenges in ...
Hongrui Zhang, Yiming Xia, Yangfan Zhang, Uma V. Ghorpade, Mingrui He, Seung Wook Shin, Xiaojing Hao, Mahesh P. Suryawanshi   +7 more
wiley   +1 more source

Effects of Polymorphism of the Growth Hormone Receptor (GHR) Gene on the Longevity and Milk Performance of White-Backed Cattle. [PDF]

Animals (Basel)
Kasprzak-Filipek K, Żółkiewski P, Chabuz W, Sawicka-Zugaj W.   +3 more
europepmc   +1 more source

Assessment and Mitigation of CRISPR‐Cas9‐Induced Nontargeted Translocations

Advanced Science, EarlyView.
Various inverted repeat elements are dispersed throughout genomes. This study reveals that these elements can cause significant chromosomal rearrangements when CRISPR editing occurs in their proximity. The risk can be mitigated by incorporating inverted repeat‐homologous segments into the CRISPR system, which represents a promising strategy for ...
Zhiyang Hou, Qiyi Yi, Mengying Wu, Lijun Wu, Fanghua Li, Ting Wang, Po Bian   +6 more
wiley   +1 more source

De Novo Reconstruction of 3D Human Facial Images from DNA Sequence

Advanced Science, EarlyView.
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao, Jiarui Li, Bingxu Zhong, Siyuan Du, Shuning Li, Manfei Zhang, Qibin Zhang, Zhongming Liang, Fan Liu, Chunman Zuo, Sijia Wang, Luonan Chen   +11 more
wiley   +1 more source