Results 231 to 240 of about 666,024 (276)

Molecular signatures of sprint, strength, and power performance: Integrating genetic, epigenetic, transcriptomic, and telomeric evidence. [PDF]

Sci Prog
El Haddouchi A, Marrouh A, Kartti S, El Fahime E, Boutayeb S, Chagar Y, Baudot C, Belyamani L, Eljaoudi R, Dakka T.   +9 more
europepmc   +1 more source

Quantifying the Single‐Cell Morphological Landscape of Cellular Transdifferentiation through Force Field Reconstruction

Advanced Science, EarlyView.
This study reconstructs the driving force field of fibroblast‐to‐neuron transdifferentiation from sparse single‐cell images by decomposing it into flux and time‐dependent potential gradient, extending the landscape‐flux framework to non‐steady‐state systems.
Chudan Yu, Chuanbo Liu, Erkang Wang, Jin Wang   +3 more
wiley   +1 more source

Distribution characteristics of MTHFR C677T gene polymorphism in Han nationality and women of childbearing age in 8 regions of Shaanxi province and a comparative analysis with other regions in China. [PDF]

Front Genet
Chen T, Song F, Sun J, Yi J, Ma W.
europepmc   +1 more source

Comment on “De Novo Reconstruction of 3D Human Facial Images from DNA Sequence”

Advanced Science, EarlyView.
This comment examines AI‐driven DNA‐based facial reconstruction, focusing on the Difface model. While such technologies promise biomedical and forensic applications, they pose significant ethical, legal, and methodological challenges. We emphasize transparency, benchmarking, and rigorous validation to avoid misinterpretation and misuse.
Jennifer K. Wagner, Nina Claessens, Caitlin M. Maloney, Peter Claes   +3 more
wiley   +1 more source

Toward a Multi-Trait Genetic Panel Targeting Training, Rehabilitation, and Chronic Disease Prevention: A Narrative Review. [PDF]

Genes (Basel)
Imperatore A, Mennitti C, De Fonzo G, Amitrano R, Gentile A, Calvanese M, Iafusco F, Coppola S, Digno M, Borrelli P, Lombardo B, Frisso G, Berni Canani R, Tinto N, D'Argenio V, Scudiero O.   +15 more
europepmc   +1 more source

Methodologies for Sample Multiplexing and Computational Deconvolution in Single‐Cell Sequencing

Advanced Science, EarlyView.
Sample multiplexing offers a critical solution for boosting throughput and minimizing batch effects in single‐cell sequencing. This review navigates the latest experimental methodologies and computational deconvolution algorithms, bridging the gap between wet‐lab design and analytical success.
Yufei Gao, Weiwei Yin, Wei Hu, Wei Chen
wiley   +1 more source

Association of GABRG2 gene polymorphisms with idiopathic generalized epilepsy in Egyptian children: a case-control study. [PDF]

Eur J Med Res
Wahba Y, Shahin D, El-Gilany AH, Yahia S, El-Tantawy N, Khodair M, Sherbiny H, Khalil H, Soheeb K.   +8 more
europepmc   +1 more source

Metabolic syndrome and ADRB3 gene polymorphism in severely obese patients from South Italy [PDF]

, 2007
C Finelli, C Nardelli, F Contaldo, F Pasanisi, G Labruna, G Oriani, G Salvatori, L Sacchetti, P Buono, R Bracale   +9 more
core  

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

Advanced Science, EarlyView.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li, Fulong Man, Jianwei Cheng, Li Chen, Yongyong Li, Haiqing Dong   +5 more
wiley   +1 more source

OXTR rs2254298 polymorphism influences escitalopram response in Generalized Anxiety Disorder: a sex-specific role for oxytocin signaling. [PDF]

Front Psychiatry
Xue L, Ni H, Dai H.
europepmc   +1 more source