Results 221 to 230 of about 727,358 (304)
Advanced Science, EarlyView.PRKCQ‐AS1 is overexpressed due to transcriptional super‐enhancers. PRKCQ‐AS1 RNA forms a complex with MSI2 protein to induce BMX mRNA stabilization and overexpression, ERK protein phosphorylation and neuroblastoma cell proliferation. Compound NSC617570 blocks PRKCQ‐AS1 binding to MSI2, leading to BMX mRNA disassociation from MSI2 protein, BMX reduction,
Sujanna Mondal +23 more
wiley +1 more source
Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 63-70, January 2023., 2023 We found that microRNA‐196b‐5p was significantly upregulated in precancerous lesions and that combining it with other microRNAs increased the accuracy of detection. Since endoscopy is associated with risk, the identification of high‐risk groups for gastric cancer is expected to make it possible to clearly identify groups that should undergo endoscopy ...
Hajime Otsu +9 more
wiley +1 more source
Cubic Phase‐Inducible Zwitterionic Phospholipids Improve the Functional Delivery of mRNA
Advanced Science, EarlyView.In this study, a chemically engineered zwitterionic phospholipids derived from 1,2‐dioleoyl‐3‐sn‐glycero‐phosphoethanolamine (DOPE), DOPE‐Cx, are designed. The DOPE‐Cx lipids induce a cubic phase upon mixing with phosphatidylcholine, facilitate membrane fusion‐mediated endosomal escape, and enhance the functional delivery of mRNA.
Kazuki Iwakawa +5 more
wiley +1 more source
Genetic polymorphism of the third component of human complement (C′3) [PDF]
, 1968 Chester A. Alper, Richard P. Propp
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Journal of Pharmacy and Pharmacology, 1970 M P Summers, R P Enever, J. E. Carless
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Genomic Insights into Post‐Domestication Expansion and Selection of Body Size in Ponies
Advanced Science, EarlyView.The authors’ research delves into the history of ponies by assembling a pony genome and integrating horse genomes. This unveils genetic connections between Asian and European pony breeds. Cis‐regulatory elements of key genes impacting body size are also identified.
Xingzheng Li +23 more
wiley +1 more source
The Rise of Chalcohalide Solar Cells: Comprehensive Insights From Materials to Devices
Advanced Science, EarlyView.This review provides a detailed overview of recent advancements in chalcohalide solar cells, focusing on structure design, material chemistry, synthesis methods, and device optimization. It also highlights future directions for improving device efficiency through innovative device architectures and synthesis techniques, addressing key challenges in ...
Hongrui Zhang +7 more
wiley +1 more source
ADAPTIVE SIGNIFICANCE OF PIGMENT POLYMORPHISMS IN COLIAS BUTTERFLIES, II. THERMOREGULATION AND PHOTOPERIODICALLY CONTROLLED MELANIN VARIATION IN Colias eurytheme [PDF]
, 1969 Ward B. Watt
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