Results 161 to 170 of about 66,871 (301)

Oxaliplatin‐induced neuropathy after total neoadjuvant therapy for rectal cancer: Dose–response relationship and impact on quality of life

International Journal of Cancer, Volume 159, Issue 1, Page 198-209, 1 July 2026.
What's New? Oxaliplatin serves a key role in the treatment of rectal cancer, though it is a significant cause of chemotherapy‐induced peripheral neuropathy. As total neoadjuvant therapy, in which all therapy is given before surgery, has become more common, understanding neuropathy has grown increasingly important. This study examined neuropathy and its
Georg W. Wurschi, Andreas Hinz, Melanie Schneider, Jan‐Niklas Becker, Bernd Frerker, Samuel M. Vorbach, Felix Ehret, Markus Diefenhardt, Fabian Schunn, Maria‐Elena von Gruben, Marcel Büttner, Elgin Hoffmann, Alexander Rühle, Josephine Beier, Simone Ferdinandus, Maike Trommer, Ezgi Ceren Sahin, Julian Hlouschek, Kynann Aninditha, Daphne Schepers von Ohlen, Justus Kaufmann, Alina Depardon, Hai Minh Ha, Christopher Kessler, Adrianna Cieslak, Simon Trommer, Alexander Fabian, Florian Rißner, Maximilian Römer, Klaus Pietschmann   +29 more
wiley   +1 more source

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri, Andrea Bordugo, Birute Burnyte, Alessandro Costetti, Maria‐Luz Couce, Luisa Diogo, Francois Feillet, D. Sean Froese, Benedetta Greco, Jean‐Louis Gueant, Luciana Hannibal, Friederike Hörster, Viktor Kožich, Giancarlo La Marca, Irini Manoli, Fanny Mochel, Lorenzo Orazi, Belén Pérez, Manuel Schiff, Bernd C. Schwahn, Ida Schwartz, Karolina M. Stepien, Jolanta Sykut‐Cegielska, Trine Tangeraas, Rolf H. Zetterström, Carlo Dionisi‐Vici, Martina Huemer   +26 more
wiley   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Polyneuropathy - Treatment [PDF]

DMW - Deutsche Medizinische Wochenschrift, 2002
B, Schlotter-Weigel, D E, Pongratz
openaire   +2 more sources

Quality of Life in Patients With Chronic Inflammatory Demyelinating Polyneuropathy

Muscle &Nerve, Volume 74, Issue 1, Page 59-67, July 2026.
ABSTRACT Introduction/Aims Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare disorder of the nervous system that detrimentally influences health‐related quality of life (HRQoL). Evidence regarding factors influencing HRQoL in CIDP is scarce.
Tobias C. Blum, Hendrik van der Wurp, David Mengel, Linda Fraune, Norbert Sommer, Mark Stettner, Björn Tackenberg, Richard Dodel   +7 more
wiley   +1 more source

Longitudinal assessment of metabolic and neurological decline in peripheral polyneuropathy over ten years. [PDF]

Future Sci OA
Azizkhojayeva D, Nuskabayeva G, Sadykova K, Turmanbayeva A, Kaldarkhan D, Mombekov N, Yerkhojayeva N, Raimova M, Yodgarova U, Sobirova S, Madenbay K, Oshibayeva A.   +11 more
europepmc   +1 more source

Variability of Sural SNAP and Peroneal CMAP Amplitudes Limits Consistent Electrodiagnosis of Chronic Axonal Polyneuropathy: A Cross‐Sectional Multicenter Study

Muscle &Nerve, Volume 74, Issue 1, Page 83-91, July 2026.
ABSTRACT Introduction/Aims Current consensus guidelines for the electrodiagnosis of polyneuropathy derive from highly standardized investigations performed in specialist centers, raising the question of whether they are equally applicable in everyday general neurology outpatient settings.
Gerjan M. van der Star, Ruben P. A. van Eijk, H. Stephan Goedee, Laurien L. Teunissen, Pieter A. van Doorn, Nicolette C. Notermans, Alexander F. J. E. Vrancken   +6 more
wiley   +1 more source

Postural Control Deficits in Patients With Chronic Inflammatory Demyelinating Polyradiculoneuropathy Undergoing Immunomodulatory Therapy

Muscle &Nerve, Volume 74, Issue 1, Page 68-76, July 2026.
ABSTRACT Introduction/Aims Despite individuals with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) often reporting impaired balance as a main concern, there is a lack of research characterizing balance impairments or evaluating whether immunomodulatory therapy improves balance.
Heather Pudwell, Kyle J. Missen, Katie Beadon, Kristine M. Chapman, Emmanuel Ogalo, Chelsea B. Smith, Michael J. Berger, Mark G. Carpenter   +7 more
wiley   +1 more source

TrkA abundance is increased in cutaneous nerves in bortezomib‐induced neuropathy

Brain Pathology, Volume 36, Issue 4, July 2026.
Cutaneous nerves in bortezomib‐induced peripheral neuropathy (BIPN) show reduced nerve fiber density, increased TrkA expression, and enhanced dermal angiogenesis, highlighting a pathological switch in NGF/TrkA signaling that may contribute to nerve damage and pain. Abstract Tropomyosin receptor kinase A (TrkA), a high‐affinity receptor for nerve growth
Yuying Jin, Nadine Cebulla, Daniel Schirmer, Eva Runau, Leon Flamm, Calvin Terhorst, Laura Jähnel, Johanna Güse, Nicola Giordani, Annett Wieser, Julian Brennecke, Annemarie Sodmann, Martin Kortüm, Robert Blum, Claudia Sommer   +14 more
wiley   +1 more source

Evaluation of serum neurofilament light chain, GFAP, and peripherin as biomarkers in hereditary transthyretin amyloidosis. [PDF]

Sci Rep
Anan I, Johannson G, Pilebro B, Wixner J, Heldestad V, Arvidsson S, Olsson M.   +6 more
europepmc   +1 more source