Results 81 to 90 of about 90,761 (279)

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

open access: yesMed Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Use of vitamin & mineral supplements in nootropic therapy for asthenic conditions and neurological disorders

open access: yesМедицинский совет, 2015
The article discusses the role of vitamin & mineral supplements in nootropic therapy, treatment of hypovitaminosis, neurological disorders, as well as in maintaining the normal function of human health in high stress.
N. V. Vakhnina, E. Y. Kalimeeva
doaj   +1 more source

Clinical, electrophysiological, and histopathological profile of biopsy-proven vasculitic neuropathy

open access: yesCHRISMED Journal of Health and Research, 2020
Background: Vasculitic neuropathies are an uncommon heterogeneous group of nerve disorders characterized by inflammation of the vasa nervorum, which may be either systemic vasculitic neuropathy (SVN) or non-SVN (NSVN).
Suchitra Deolalikar   +6 more
doaj   +1 more source

Laryngeal paralysis in dogs : an update on recent knowledge [PDF]

open access: yes, 2013
Laryngeal paralysis is the effect of an inability to abduct the arytenoid cartilages during inspiration, resulting in respiratory signs consistent with partial airway obstruction.
De Rooster, Hilde   +4 more
core   +4 more sources

Types of Pain in Multiple System Atrophy

open access: yesMovement Disorders, EarlyView.
Abstract Background Pain affects up to 87% of people with multiple system atrophy (MSA), but it remains unclear which types of pain contribute most to the overall burden. Objective To estimate the frequency of different types of pain in MSA individuals.
Nicole Campese   +19 more
wiley   +1 more source

Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults. [PDF]

open access: yes, 2019
Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are involved in energy metabolism and biosynthesis of nucleic acids whereas others ...
Adams   +154 more
core   +2 more sources

Long‐Term Outcomes of Deep Brain Stimulation in Woodhouse–Sakati Syndrome

open access: yesMovement Disorders, EarlyView.
Abstract Background Woodhouse–Sakati syndrome (WSS) is a rare autosomal recessive disease with distinctive neuroendocrine manifestations, with dystonia being the most common. No clear guidelines are available for the treatment of dystonia in WSS. Objective The aim was to analyze the impact of deep brain stimulation (DBS) on WSS‐associated dystonia ...
Hend Alhodaif   +5 more
wiley   +1 more source

Differential binding patterns of anti-sulfatide antibodies to glial membranes [PDF]

open access: yes, 2018
Sulfatide is a major glycosphingolipid in myelin and a target for autoantibodies in autoimmune neuropathies. However neuropathy disease models have not been widely established, in part because currently available monoclonal antibodies to sulfatide may ...
Barrie, Jennifer A.   +8 more
core   +1 more source

Uncovering the Mechanism of Aggregation of Human Transthyretin. [PDF]

open access: yes, 2015
The tetrameric thyroxine transport protein transthyretin (TTR) forms amyloid fibrils upon dissociation and monomer unfolding. The aggregation of transthyretin has been reported as the cause of the life-threatening transthyretin amyloidosis.
Cascio, Duilio   +9 more
core   +2 more sources

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

open access: yesMicrobiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai   +6 more
wiley   +1 more source

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