Methods of partitioning, biogenesis, and selecting for natural and engineered CoA-RNA [PDF]
More than a decade ago, RNAs with NAD+, CoA, and acylated CoA caps were identified. Since then, studies have described NAD+'s protective, cap-like function in bacteria and its role in promoting mRNA degradation in eukaryotic cells.
Lucas, Jordyn Kaye
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, 2022 Recent acknowledgment that multidrug resistant Stenotrophomonas maltophilia strains can cause severe infections has led to increasing global interest in addressing its pathogenicity.
Bridge, Wallace +4 more
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New Insights into the Phylogeny and Molecular Classification of Nicotinamide Mononucleotide Deamidases [PDF]
, 2013 Nicotinamide mononucleotide (NMN) deamidase is one of the key enzymes of the bacterial pyridine nucleotide cycle (PNC). It catalyzes the conversion of NMN to nicotinic acid mononucleotide, which is later converted to NAD+ by entering the Preiss-Handler ...
Agustín Sola-Carvajal +47 more
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Molecular Cloning of Sugarcane Mosaic Virus Complementary-Dna: Use as a Probe for the Detection of Virus Infection and Viral-Rnas. [PDF]
, 1983 DNA complementary (cDNA) to the RNA genome of sugarcane mosaic virus strain H (SCMV-H) was synthesized using avian myeloblastosis virus reverse transcriptase and oligo(dT) as primer. Second strand synthesis used the same enzyme and oligo(dG) primer after
French, Roy Chester
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Spaceflight Alters Bacterial Gene Expression and Virulence and Reveals Role for Global Regulator Hfq [PDF]
A comprehensive analysis of both the molecular genetic and phenotypic responses of any organism to the spaceflight environment has never been accomplished due to significant technological and logistical hurdles.
Bober, R. +24 more
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Analysis of the Arabidopsis Polyadenylation Factors PAP1, CstF64 and CstF77 and their characteristic inter-relationship [PDF]
, 2009 3’-end modification by polyadenylation is a ubiquitous feature of almost all eukaryotic mRNA species and is catalyzed by a consortium of enzymes, the polyadenylation factors.
Bandyopadhyay, Amrita
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RNA-basierte Kontrolle der Expression des Typ III Sekretionssystems von Yersinia pseudotuberculosis [PDF]
, 2017 Expression of Ysc-Yop type III secretion system requires a tight regulation, which is conferred by two RNA-binding proteins YopD and CsrA. The underlying study demonstrated that expression of the transcriptional master regulator lcrF of the Ysc-Yop T3SS ...
Hoßmann, Jörn
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Transcriptional profiling of sweetpotato (Ipomoea batatas) roots indicates down-regulation of lignin biosynthesis and up-regulation of starch biosynthesis at an early stage of storage root formation [PDF]
, 2013 Background: The number of fibrous roots that develop into storage roots determines sweetpotato yield. The aim of the present study was to identify the molecular mechanisms involved in the initiation of storage root formation, by performing a detailed ...
Althan, Leviah +10 more
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More than an RNA matchmaker: Expanding the roles of Hfq into ribosome biogenesis [PDF]
, 2018 Ribosome biogenesis is a complex process involving multiple factors. The work described here is primarily centered in the study of ribosomal RNA, highlighting its central role in translation regulation.
dos Santos, Ricardo F.
core
Structural and functional characterization of Clp1, a eukaryotic RNA‐specific polynucleotide kinase [PDF]
, 2013 Polynucleotide kinases (PNKs) are crucial enzymes involved in DNA and RNA repair, RNA maturation, as well as in RNA degradation processes. These enzymes have a conserved PNK domain, showing structural homology to the classical fold of P-loop kinases ...
Dikfidan, Aytac
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