Results 1 to 10 of about 88,763 (155)

Protein-Protein Interactions in Base Excision Repair. [PDF]

Biomolecules
Rathnaiah G, Sweasy JB.
europepmc   +1 more source

Mechanism and potential therapeutic strategies of genetic abnormalities involved in deoxyribonucleic acid double-strand breaks leading to the development of human non-obstructive azoospermia. [PDF]

Reprod Biol Endocrinol
Wang X, Zhang Y, Zhu Z, Wang C, Yao M, Xu H, Zhang Z, Ping H, Xia X, Meng K, Gao F, Yuan J.   +11 more
europepmc   +1 more source

XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sites. [PDF]

Nucleic Acids Res
Lin X, Leung KSK, Wolfe KF, Call N, Bhandari SK, Huang X, Lee BJ, Tomkinson AE, Zha S.   +8 more
europepmc   +1 more source

USP37 protects mammalian cells during DNA replication stress by counteracting CUL2^LRR1and TRAIP

Villa F, Ainsworth J, Labib KP.
europepmc   +1 more source

Polynucleotide ligase in mouse cells infected by polyoma virus

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972
Abstract 1. The properties of polynucleotide ligase from mouse cells infected with polyoma virus, and from uninfected mouse cells, were studied in order to investigate the possible involvement of ligase in polyoma DNA replication. 2. Two procedures for the assay of polynucleotide ligase were used to detect ligase in extracts of mouse embryo cells ...
Peter Beard
openaire   +3 more sources

The polynucleotide ligase and RNA capping enzyme superfamily of covalent nucleotidyltransferases

Current Opinion in Structural Biology, 2004
ATP- and NAD(+)-dependent DNA ligases, ATP-dependent RNA ligases and GTP-dependent mRNA capping enzymes comprise a superfamily of proteins that catalyze nucleotidyl transfer to polynucleotide 5' ends via covalent enzyme-(lysyl-N)-NMP intermediates. The superfamily is defined by five peptide motifs that line the nucleotide-binding pocket and contribute ...
Stewart, Shuman, Christopher D, Lima
openaire   +3 more sources

Discovery of potential inhibitors targeting the kinase domain of polynucleotide kinase/phosphatase (PNKP): Homology modeling, virtual screening based on multiple conformations, and molecular dynamics simulation

Comput. Biol. Chem., 2021
In recent years, the level of interest has been increased in developing the DNA-repair inhibitors, to enhance the cytotoxic effects in the treatment of cancers.
Jingyu Zhu, Haoer Zhang, Lei Jia, Lijun Ma, Lei Xu, Yun Chen, Yanfei Cai, Huazhong Li, Gang Huang, Jian Jin   +9 more
semanticscholar   +1 more source

A convenient solid-state substrate for assays of polynucleotide ligase

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1971
U. Bertazzoni, F. Campagnari, U. De Luca
openaire   +2 more sources

Polynucleotide Ligase and φX174 Single Strand Synthesis

Nature New Biology, 1971
A DNA ligase mutant of E. coli when infected with φX174 produces linear single strands which appear in an intracellular pool and in phage particles. The linear single strands, which are infectious in a spheroplast assay, seem to be a normal intermediate in progeny DNA synthesis.
R W, Schekman, D S, Ray
openaire   +2 more sources