Abstract In this descriptive analysis of the 21‐year follow‐up data from the SHIP‐START cohort and the 7‐year follow‐up data from the SHIP‐TREND cohort, we report the progression of clinical attachment levels (CAL), age effects on CAL change, and a detailed description of CAL progression and remission. At baseline, 4307 and 4420 persons participated in
Thomas Kocher +4 more
wiley +1 more source
Prevalence of polypharmacy and drug interactions in geriatric patients: A cross-sectional study from India. [PDF]
Khaiser UF +9 more
europepmc +1 more source
Plain Language Summary This study shows that galcanezumab is equally effective and well‐tolerated in patients aged 65 and older as in younger patients, with a higher proportion of excellent responders in older patients. Despite having more baseline headache days, older patients responded well to the treatment, with age being linked to better outcomes ...
Julia Peris‐Subiza +27 more
wiley +1 more source
Association of Polypharmacy and Bone Mineral Density: A Cross-Sectional Analysis of Geriatric Inpatients in Germany. [PDF]
Kopanos S +4 more
europepmc +1 more source
Integrating gepants into clinical practice for the acute treatment of migraine
Abstract Objective To assess the role of small‐molecule calcitonin gene–related peptide receptor antagonists (gepants) in the acute treatment of migraine, particularly in relation to triptan treatments. Background Triptans have established efficacy and are widely prescribed for the acute treatment of migraine.
Richard B. Lipton +4 more
wiley +1 more source
Polypharmacy, determinants, and adverse outcomes in elderly patients with heart failure: a multicenter retrospective cohort study of 7,361 subjects. [PDF]
Zhong W +6 more
europepmc +1 more source
Abstract Objectives To characterize real‐world treatment switching in France to bictegravir (BIC or B) or dolutegravir (DTG)‐based regimens with a focus on treatment persistence, effectiveness (HIV‐1 RNA ≤50 copies/ml) and particular attention to the prevalence and incidence of comorbidities. Methods People living with HIV from the prospective ANRS‐CO3‐
O. Leleux +15 more
wiley +1 more source
Association between polypharmacy at the emergency department and long-term mortality in critically ill older patients receiving mechanical ventilation: a single-center retrospective cohort study. [PDF]
Nakamura Y +5 more
europepmc +1 more source
ABSTRACT Oral dryness is common in persons with untreated obstructive sleep apnoea (OSA) as well as in those using positive airway pressure (PAP). OSA with or without PAP treatment could therefore be a risk factor of dental caries. Objectives To describe and compare the prevalence of dental caries among persons with or without PAP‐treated OSA.
H. Ahonen +6 more
wiley +1 more source
Addressing a Common Misconception of Simple Additive and Cumulative Drug Inhibition: Multiple Weak Inhibitors of Common Metabolic Pathway Do Not Pose a Strong Interaction Risk! [PDF]
Scotcher D +3 more
europepmc +1 more source

