Results 111 to 120 of about 240,390 (129)
Volatile Oil From <i>Acorus Gramineus</i> Rhizoma Synergizes with Crebanine to Alleviate Oxidative Stress and Endoplasmic Reticulum Stress in Myocardial Ischemia-Reperfusion Injury by Suppressing GRP78-PERK/ATF6-CHOP and MAPK-NF-κB-TNF-α Signaling Pathways. [PDF]
J Inflamm ResZha L +8 more
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Effects of light intensity on growth and leaf functional trait plasticity of <i>Paris polyphylla var. yunnanensis</i>. [PDF]
Plant Signal BehavZi G, Li Q, Leng Y, Hu J.
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Industrial Crops and Products, 2020
Abstract Paris polyphylla Smith is a perennial medicinal plant that is wildly distributed in China, and polyphyllin is the representative medicinal ingredient from the rhizome of this plant. To date, the mechanism of steroidal saponin biosynthesis in P. polyphylla is still unclear.
Xinjie Yang, Xinbo Shi
exaly +2 more sources
Abstract Paris polyphylla Smith is a perennial medicinal plant that is wildly distributed in China, and polyphyllin is the representative medicinal ingredient from the rhizome of this plant. To date, the mechanism of steroidal saponin biosynthesis in P. polyphylla is still unclear.
Xinjie Yang, Xinbo Shi
exaly +2 more sources
An Improved Synthesis of the Saponin, Polyphyllin D
Carbohydrate Research, 2001 Polyphyllin D, namely diosgenyl alpha -L-rhamnopyranosyl-(1->2)-[(alpha -L-arabinofuranosyl)-(1->4)]-beta -D-glucopyranoside, was synthesized from diosgenyl-beta -D-glucopyranoside in four steps and in 30% overall yield, taking advantage of ...
Kwok Pui Fung, Biao Yu, Xiuwen Han
exaly +1 more source
Synthesis of Three Diosgenyl Saponins: Dioscin, Polyphyllin D, and Balanitin 7
Carbohydrate Research, 1999 Dioscin, polyphyllin D, and balanitin 7, which belong to a group of structurally similar diosgenyl saponins with promising bioactivities, were synthesized by stepwise glycosylation. (C) 1999 Elsevier Science Ltd.
Biao Yu, Xiuwen Han, Shaojiang Deng
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Two rhamnosyltransferases for de novo biosynthesis of polyphyllins in Nicotiana benthamiana
The Plant JournalSUMMARYPolyphyllins, a prominent class of steroidal saponins in Paris species, owe their diverse bioactivities to their sugar unit configurations, though their glycosylation pathways remain poorly understood. Here, we identified and characterized two UDP‐rhamnosyltransferases, PpUGT73YD1 and PpUGT738A2, using heterologous expression systems.
Wei Song +7 more
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ACS Synthetic Biology
Polyphyllin V (PPV) is a pharmaceutically valuable steroidal saponin with extremely low natural abundance, severely limiting its research and application. Here we established an efficient plant-based production platform for PPV in Nicotiana benthamiana through systematic optimization of glycosyltransferases and UDP-sugar metabolism.
Wei Song +10 more
openaire +2 more sources
Polyphyllin V (PPV) is a pharmaceutically valuable steroidal saponin with extremely low natural abundance, severely limiting its research and application. Here we established an efficient plant-based production platform for PPV in Nicotiana benthamiana through systematic optimization of glycosyltransferases and UDP-sugar metabolism.
Wei Song +10 more
openaire +2 more sources
Abstract Polyphyllins, a class of isospirostan-type steroidal saponins, exhibit potent cytotoxicity against a variety range of cancer cells. Although extensive research efforts have been made, the complete biosynthetic pathway of these compounds remains unclear.
Yuxin Yang +9 more
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Yuxin Yang +9 more
openaire +1 more source