Results 61 to 70 of about 59,670 (326)

Autophagy-deficient breast cancer shows early tumor recurrence and escape from dormancy [PDF]

open access: yes, 2018
Breast cancer patients who initially respond to cancer therapies often succumb to distant recurrence of the disease. It is not clear why people with the same type of breast cancer respond to treatments differently; some escape from dormancy and relapse ...
Manjili, Masoud H.
core   +1 more source

Escaping Constraints to Innovate: Maternal Neofunctionalization in a HoxB4 Duplicate

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Whole‐genome duplication in Xenopus laevis generated duplicated Hox genes that are largely constrained in sequence and developmental expression. However, HoxB4L uniquely acquired maternal expression through cis‐regulatory and protein structural divergence, illustrating how gene duplication enables transcription factors to escape pleiotropic constraints
Júlia de Lima Carvalho   +2 more
wiley   +1 more source

The Formation of a Novel Intergeneric Hybrid Fish Derived from Megalobrama amblycephala (♀) × Culter dabryi (♂)

open access: yesAnimals
Distant hybridization in fish serves to integrate the genetic material from two distinct, distantly related species. In this study, we successfully produced a new hybrid fish (BG) through the intergeneric hybridization of blunt snout bream (Megalobrama ...
Zhifeng Zhou   +14 more
doaj   +1 more source

Polyploid Speciation

open access: yes, 2016
Genome duplication represents a dramatic, yet relatively common, genomic change, having occurred in the evolutionary history of angiosperms, vertebrates, and yeast, among many other groups. The result of such duplications ('polyploidy,' the existence of multiple sets of chromosomes within the genome) has long been recognized and was implicated as a ...
Rothfels, CJ, Otto, SP
openaire   +3 more sources

Polyploidization in Liver Tissue

open access: yesThe American Journal of Pathology, 2014
Polyploidy (alias whole genome amplification) refers to organisms containing more than two basic sets of chromosomes. Polyploidy was first observed in plants more than a century ago, and it is known that such processes occur in many eukaryotes under a variety of circumstances.
Gentric, Géraldine, Desdouets, Chantal
openaire   +3 more sources

Characterization of the polymorphism detected for the granule‐bound starch synthase (WX gene) in wild einkorn wheat

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The WX gene encodes the granule‐bound starch synthase I or waxy protein, which is the sole enzyme responsible for amylose synthesis in wheat seeds. Wild einkorn wheat (Triticum monococcum L. ssp. aegilopoides Link em. Thell.) could be an important source of variation for this gene. RESULTS This study assessed the WX gene variability
Juan B. Alvarez   +2 more
wiley   +1 more source

Integrated Analysis of Phenotypic and Hepatic Transcriptomic Profiles Reveals Enhanced Cold Tolerance in Triploid Crucian Carp

open access: yesFishes
Cold stress poses a critical threat to fish survival by triggering metabolic dysfunction, oxidative damage, immune suppression, and apoptosis. However, hybrid polyploid fish triploid crucian carp (3nRCR, 3n = 150) demonstrate superior stress tolerance ...
Suifei Tao   +9 more
doaj   +1 more source

Mapping a Novel Black Spot Resistance Locus in the Climbing Rose Brite Eyes™ (‘RADbrite’)

open access: yesFrontiers in Plant Science, 2018
Rose black spot, caused by Diplocarpon rosae, is one of the most devastating foliar diseases of cultivated roses (Rosa spp.). The globally distributed pathogen has the potential to cause large economic losses in the outdoor cultivation of roses ...
Jason D. Zurn   +5 more
doaj   +1 more source

Transgressivity in Key Functional Traits Rather Than Phenotypic Plasticity Promotes Stress Tolerance in A Hybrid Cordgrass [PDF]

open access: yes, 2019
Hybridization might promote offspring fitness via a greater tolerance to environmental stressors due to heterosis and higher levels of phenotypic plasticity.
Castillo Segura, Jesús Manuel   +3 more
core   +1 more source

Friends or foes? Polyploidy and competition in a grassland geophyte

open access: yesOikos, EarlyView.
Previous studies have suggested polyploids may possess a competitive advantage over diploids, due to their larger size, increased vigour or ability to better respond to abiotic stress. However, few studies have tested the effect of polyploidy on competitive ability directly, and only relatively recently has this oversight begun to be addressed. Here we
Damian Vaz de Sousa   +3 more
wiley   +1 more source

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