Results 1 to 10 of about 82,673 (166)

Management of familial adenomatous polyposis and MUTYH-associated polyposis; new insights

Bailliere's Best Practice and Research in Clinical Gastroenterology, 2022
Familial adenomatous polyposis (FAP) and MUTYH-associated polyposis (MAP) are rare inherited polyposis syndromes with a high colorectal cancer (CRC) risk.
Arthur Aelvoet, Evelien Dekker, Luigi Ricciardiello   +2 more
exaly   +2 more sources

Update on genetic predisposition to colorectal cancer and polyposis

Molecular Aspects of Medicine, 2019
The present article summarizes recent developments in the characterization of genetic predisposition to colorectal cancer (CRC). The main themes covered include new hereditary CRC and polyposis syndromes, non-CRC hereditary cancer genes found mutated in ...
Pilar Garre Rubio, Trinidad Caldes, Clara Ruiz-Ponte   +2 more
exaly   +2 more sources

Comparative Histopathological Changes Between Primary Versus Recurrent Rhinosinusitis with Nasal Polyposis [PDF]

International Journal of Medical Arts, 2021
Background: Chronic rhinosinusitis associated with nasal polypi [CRSwNP] is one of the two major chronic rhinosinusitis phenotypes. The histopathological changes of such condition may differ between primary and chronic types.Aim of the work: To ...
Wael Fawzy Ismaiel, Ahmed Abd Alrahman Ibrahim, Sami Abdullah Mohammed   +2 more
doaj   +1 more source

Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on Colorectal Cancer.

Gastroenterology, 2022
The gastrointestinal hamartomatous polyposis syndromes are rare, autosomal dominant disorders associated with an increased risk of benign and malignant intestinal and extraintestinal tumors.
C. Boland, Gregory E. Idos, C. Durno, F. Giardiello, Joseph C. Anderson, C. Burke, J. Dominitz, S. Gross, Samir Gupta, B. Jacobson, Swati G. Patel, A. Shaukat, S. Syngal, D. Robertson   +13 more
semanticscholar   +2 more sources

Morphological Analyses of Colorectal Adenocarcinomas in Japanese Familial Adenomatous Polyposis Patients

Journal of the Anus, Rectum and Colon, 2022
Objectives: This retrospective study was conducted to clarify the morphological characteristics of colorectal cancer (CRC) in Japanese familial adenomatous polyposis (FAP) patients.
Yozo Suzuki, Fumio Ishida, Hideyuki Ishida, Hideki Ueno, Hirotoshi Kobayashi, Tatsuro Yamaguchi, Tsuyoshi Konishi, Yukihide Kanemitsu, Takao Hinoi, Yasuhiro Inoue, Naohiro Tomita, Kenichi Sugihara   +11 more
doaj   +1 more source

Small Intestinal Polyp Burden in Pediatric Peutz–Jeghers Syndrome Assessed through Capsule Endoscopy: A Longitudinal Study

Children, 2023
The management of pediatric Peutz–Jeghers Syndrome (PJS) focuses on the prevention of intussusception complicating small intestinal (SI) polyposis. This hinges on the accurate appraisal of the polyp burden to tailor therapeutic interventions.
Jeremy Stewart, Nathan R. Fleishman, Vincent S. Staggs, Mike Thomson, Nicole Stoecklein, Caitlin E. Lawson, Michael P. Washburn, Shahid Umar, Thomas M. Attard   +8 more
doaj   +1 more source

Current clinical practice for familial adenomatous polyposis in Japan: A nationwide multicenter study

Annals of Gastroenterological Surgery, 2022
Introduction In Japanese patients with familial adenomatous polyposis (FAP), colectomy tends to be postponed or avoided. Aim This study aimed to clarify the current clinical practice from a Japanese multicenter cohort study database.
Takaaki Matsubara, Naohito Beppu, Masataka Ikeda, Hideyuki Ishida, Yoji Takeuchi, Toshiya Nagasaki, Akinari Takao, Kazuhito Sasaki, Kiwamu Akagi, Tomoya Sudo, Hideki Ueno, Tatsuro Yamaguchi, Naohiro Tomita, Yoichi Ajioka   +13 more
doaj   +1 more source

Mono- and biallelic germline variants of DNA glycosylase genes in colon adenomatous polyposis families from two continents

Frontiers in Oncology, 2022
Recently, biallelic germline variants of the DNA glycosylase genes MUTYH and NTHL1 were linked to polyposis susceptibility. Significant fractions remain without a molecular explanation, warranting searches for underlying causes.
Alisa Petriina Olkinuora, Andrea Constanza Mayordomo, Andrea Constanza Mayordomo, Anni Katariina Kauppinen, María Belén Cerliani, Mariana Coraglio, Ávila Karina Collia, Alejandro Gutiérrez, Karin Alvarez, Alessandra Cassana, Francisco Lopéz-Köstner, Federico Jauk, Hernán García-Rivello, Ari Ristimäki, Ari Ristimäki, Laura Koskenvuo, Anna Lepistö, Anna Lepistö, Taina Tuulikki Nieminen, Carlos Alberto Vaccaro, Carlos Alberto Vaccaro, Walter Hernán Pavicic, Walter Hernán Pavicic, Päivi Peltomäki   +23 more
doaj   +1 more source

Efficacy and safety of omalizumab in nasal polyposis: two randomized phase III trials.

Journal of Allergy and Clinical Immunology, 2020
BACKGROUND Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by IgE hyperproduction and eosinophilic inflammation. The anti-IgE antibody, omalizumab, has demonstrated efficacy in patients with CRSwNP and comorbid asthma previously ...
P. Gevaert, T. Omachi, J. Corren, J. Mullol, Joseph K. Han, Stella E. Lee, D. Kaufman, M. Ligueros‐Saylan, M. Howard, Rui Zhu, R. Owen, Kit Wong, L. Islam, C. Bachert   +13 more
semanticscholar   +1 more source

Clinical characteristics and risk factors related to polyposis recurrence and advanced neoplasm development among patients with non-hereditary colorectal polyposis [PDF]

Intestinal Research, 2023
Background/Aims Patients with more than 10 cumulative polyps might involve a greater genetic risk of colorectal neoplasia development. However, few studies have investigated the risk factors of polyposis recurrence and development of advanced neoplasms ...
Jihun Jang, Jihye Park, Soo Jung Park, Jae Jun Park, Jae Hee Cheon, Tae Il Kim   +5 more
doaj   +1 more source