Results 101 to 110 of about 935 (127)
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Human Physiology, 2020
Short-term in vitro exposure of a chaotropic reagent to native class G immunoglobulins can significantly increase the activity of anti-endotoxin immunity and cause a decrease in the ability of effector cells for enterobacteria lipopolysaccharides (LPS). This leads to reducing the LPS-dependent activation of these cells and subsequent inflammation. This
Vladimir Beloglazov +2 more
exaly +2 more sources
Short-term in vitro exposure of a chaotropic reagent to native class G immunoglobulins can significantly increase the activity of anti-endotoxin immunity and cause a decrease in the ability of effector cells for enterobacteria lipopolysaccharides (LPS). This leads to reducing the LPS-dependent activation of these cells and subsequent inflammation. This
Vladimir Beloglazov +2 more
exaly +2 more sources
Blood, 2010
Multiple attempts have been made in the past 2 decades to delineate the antigen specificity of tumor immunoglobulins expressed by mucosa-associated lymphoid tissue (MALT) lymphoma. These studies have produced rather discrepant results, which may be attributable to the different approaches to tumor-
Müller Anne
exaly +3 more sources
Multiple attempts have been made in the past 2 decades to delineate the antigen specificity of tumor immunoglobulins expressed by mucosa-associated lymphoid tissue (MALT) lymphoma. These studies have produced rather discrepant results, which may be attributable to the different approaches to tumor-
Müller Anne
exaly +3 more sources
Polyreactive immunoglobulins display diversity in binding site topology
Immunotechnology: an International Journal of Immunological Engineering, 1996exaly +2 more sources
Diverse binding site structures revealed in homology models of polyreactive immunoglobulins
Journal of Computer-Aided Molecular Design, 1997We describe here computer-assisted homology models of the combining site structure of three polyreactive immunoglobulins. Template-based models of Fv (VL-VH) fragments were derived for the surface IgM expressed by the malignant CD5 positive B cells from three patients with chronic lymphocytic leukaemia (CLL).
Paul A. Ramsland +3 more
openaire +4 more sources
[Properties of polyreactive immunoglobulins].
Ukrainskii biokhimicheskii zhurnal (1978), 1994Some biological properties of polyreactive antibodies (PRABs) from the serum of mice, rabbit and cattle are investigated. Optimal parameters of the activation process are determined. It is shown that solution of KSCN (potassium rhodanide) more effectively impedes interaction of PRABs with the antigen on the immunological plate than interaction between ...
S A, Bobrovnik, A V, Marinets
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[Transformation of serum immunoglobulins to polyreactive antibodies].
Ukrainskii biokhimicheskii zhurnal (1978), 1998In order to elucidate the mechanism of induction of serum immunoglobulins polyreactive properties by chaotropic ions, gel-chromatography of immunoglobulins in the medium containing 3.3 M KSCN, has been done. It was found that the transformation of serum immunoglobulins to polyreactive antibodies, which could react with different serological unrelated ...
S A, Bobrovnik +2 more
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[Ligand-induced structuring of polyreactive immunoglobulins].
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 2004The influence of several hydrophobic compounds with different structures on the binding of native and chaotropically modified bovine immunoglobulins to native and denatured nonspecific protein immobilized on the surface is researched. It is shown that the character of binding depends on the amount and mutual location of hydrophobic nuclei in the ...
L V, Il'ina, S V, Verevka
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Developmental & Comparative Immunology, 2015
Urodele amphibians are an interesting model because although they possess the cardinal elements of the vertebrate immune system, their immune response is apparently subdued. This phenomenon, sometimes regarded as a state of immunodeficiency, has been attributed by some authors to limited antibody diversity.
Coralie, Fonte +3 more
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Urodele amphibians are an interesting model because although they possess the cardinal elements of the vertebrate immune system, their immune response is apparently subdued. This phenomenon, sometimes regarded as a state of immunodeficiency, has been attributed by some authors to limited antibody diversity.
Coralie, Fonte +3 more
openaire +2 more sources
Ukrainskii biokhimicheskii zhurnal (1978), 1998
It was shown that polyreactive properties of natural serum immunoglobulins or some monoclonal antibodies (i.e. their ability of binding to various antigenically dissimilar antigens) can be induced by the treatment with chaotropic ions (3.5 M KSCN, 5-30 min at 20 (C).
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It was shown that polyreactive properties of natural serum immunoglobulins or some monoclonal antibodies (i.e. their ability of binding to various antigenically dissimilar antigens) can be induced by the treatment with chaotropic ions (3.5 M KSCN, 5-30 min at 20 (C).
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[Complement-binding and immuno-modulating properties of polyreactive immunoglobulins].
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 2004New data concerning biological properties of polyreactive immunoglobulins (PRIG) were obtained as a result of treatment of mouse serum immunoglobulins by 4 M KSCN and are presented in the paper. In particular, the capacity of PRIG to bind C1q, the subunit of the first component of complement was studied. It was shown that PRIG's binding capacity to C1q
S A, Bobrovnik +3 more
openaire +1 more source