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The different factors influence on the serum immunoglobulms transformation into polyreactive immunoglobulins and their interaction with antigens [PDF]
Biopolymers and Cell, 1999 Найдены оптимальные условия для процесса, усиления активности сывороточных палиреактиекых иммуноглобулинов (ПРИГ) с помощью резкого сдвига рН или их обработки хаотропными ионами.
S A Bobrovnik
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Polyreactive immunoglobulins display diversity in binding site topology
Immunotechnology: an International Journal of Immunological Engineering, 1996 exaly +3 more sources
Blood, 2010 Multiple attempts have been made in the past 2 decades to delineate the antigen specificity of tumor immunoglobulins expressed by mucosa-associated lymphoid tissue (MALT) lymphoma. These studies have produced rather discrepant results, which may be attributable to the different approaches to tumor-
Anne Müller, Müller Anne
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Human Physiology, 2020
Short-term in vitro exposure of a chaotropic reagent to native class G immunoglobulins can significantly increase the activity of anti-endotoxin immunity and cause a decrease in the ability of effector cells for enterobacteria lipopolysaccharides (LPS). This leads to reducing the LPS-dependent activation of these cells and subsequent inflammation. This
N V Khimich +2 more
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Short-term in vitro exposure of a chaotropic reagent to native class G immunoglobulins can significantly increase the activity of anti-endotoxin immunity and cause a decrease in the ability of effector cells for enterobacteria lipopolysaccharides (LPS). This leads to reducing the LPS-dependent activation of these cells and subsequent inflammation. This
N V Khimich +2 more
exaly +2 more sources
[Properties of polyreactive immunoglobulins].
Ukrainskii biokhimicheskii zhurnal (1978), 1994Some biological properties of polyreactive antibodies (PRABs) from the serum of mice, rabbit and cattle are investigated. Optimal parameters of the activation process are determined. It is shown that solution of KSCN (potassium rhodanide) more effectively impedes interaction of PRABs with the antigen on the immunological plate than interaction between ...
S A, Bobrovnik, A V, Marinets
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[Transformation of serum immunoglobulins to polyreactive antibodies].
Ukrainskii biokhimicheskii zhurnal (1978), 1998In order to elucidate the mechanism of induction of serum immunoglobulins polyreactive properties by chaotropic ions, gel-chromatography of immunoglobulins in the medium containing 3.3 M KSCN, has been done. It was found that the transformation of serum immunoglobulins to polyreactive antibodies, which could react with different serological unrelated ...
S A, Bobrovnik +2 more
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[Ligand-induced structuring of polyreactive immunoglobulins].
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 2004The influence of several hydrophobic compounds with different structures on the binding of native and chaotropically modified bovine immunoglobulins to native and denatured nonspecific protein immobilized on the surface is researched. It is shown that the character of binding depends on the amount and mutual location of hydrophobic nuclei in the ...
L V, Il'ina, S V, Verevka
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Transplant ImmunologyChronic rejection remains an obstacle to long-term allograft survival. Donor-specific anti-HLA antibodies (DSA) play a significant role in causing chronic antibody-mediated allograft rejection. Exposure to mismatched HLA antigens via transfusion, pregnancy, or transplanted tissue has been described in the literature as an immunogenic stimulus of anti ...
Steven D, Heron +2 more
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Developmental & Comparative Immunology, 2015
Urodele amphibians are an interesting model because although they possess the cardinal elements of the vertebrate immune system, their immune response is apparently subdued. This phenomenon, sometimes regarded as a state of immunodeficiency, has been attributed by some authors to limited antibody diversity.
Coralie, Fonte +3 more
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Urodele amphibians are an interesting model because although they possess the cardinal elements of the vertebrate immune system, their immune response is apparently subdued. This phenomenon, sometimes regarded as a state of immunodeficiency, has been attributed by some authors to limited antibody diversity.
Coralie, Fonte +3 more
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Ukrainskii biokhimicheskii zhurnal (1978), 1998
It was shown that polyreactive properties of natural serum immunoglobulins or some monoclonal antibodies (i.e. their ability of binding to various antigenically dissimilar antigens) can be induced by the treatment with chaotropic ions (3.5 M KSCN, 5-30 min at 20 (C).
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It was shown that polyreactive properties of natural serum immunoglobulins or some monoclonal antibodies (i.e. their ability of binding to various antigenically dissimilar antigens) can be induced by the treatment with chaotropic ions (3.5 M KSCN, 5-30 min at 20 (C).
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