Plant-Derived Saponin and Polysaccharide Vaccine Adjuvants: Structure-Activity Relationships and Immune-Enhancement Strategies. [PDF]
Lao Y, Wang Z, Tian Y, Sun J, Gong L.
europepmc +1 more source
This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang +10 more
wiley +1 more source
Zein Protein Nanoparticles: Fabrication and Rheology of Their Dispersions in Polysaccharides. [PDF]
Li S, Pal R.
europepmc +1 more source
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim +5 more
wiley +1 more source
Ultrasonic modification on the physicochemical properties, structure characterizations, and intestinal barrier-protective activities of raspberry polysaccharides. [PDF]
Deng Q +7 more
europepmc +1 more source
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty +4 more
wiley +1 more source
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin +7 more
wiley +1 more source
Edible Mushroom Polysaccharides as Functional Food Ingredients for Metabolic Health: Preparation, Techno-Functional Behavior, and Requirements for Translation. [PDF]
Chen M +5 more
europepmc +1 more source
Porcupine‐Quill‐Inspired Shape‐Morphing Biointerfaces Disassemble Biofilms
A porcupine‐spine‐inspired dynamic offensive bio‐interface is developed for active biofilm disassembly. By coupling electrically driven nano‐dagger penetration with light‐triggered ROS generation, the surface overcomes the passive limitations of conventional mechano‐bactericidal topographies, achieving near‐complete biofilm eradication, strong ...
Feng Qian +10 more
wiley +1 more source
Botanical polysaccharides as veterinary vaccine adjuvants: structure, receptors, and translational limits. [PDF]
Guan R, Yang C.
europepmc +1 more source

