Results 81 to 90 of about 233,729 (274)

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia   +7 more
wiley   +1 more source

Screening, Identification and Conditions Optimization of High Chitosanase Producing Strains, and Analysis of Its Enzymatic Properties

open access: yesShipin gongye ke-ji
To screen and identify high chitosanase producing strains and to optimize the fermentation condition and analyze the enzymatic properties of the target strain.
Ying LIANG   +8 more
doaj   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

Supercritical Fluid‐Processed Multifunctional Hybrid Decellularized Extracellular Matrix with Chitosan Hydrogel for Improving Photoaged Dermis Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
These findings advance tissue repair by offering a multifunctional filler that improves large‐scale volume retention, elasticity, and support for vascularized tissue growth. The decellularized extracellular matrix (dECM)‐based material provides low injection force and minimizes swelling, ensuring sustained volume. Combining CMC with supercritical fluid‐
Seol‐Ha Jeong   +6 more
wiley   +1 more source

Infectious bursal disease virus affecting interferon regulatory factor 7 signaling through VP3 protein to facilitate viral replication

open access: yesFrontiers in Cellular and Infection Microbiology
Interferon regulatory factor 7 (IRF7)-mediated type I interferon antiviral response is crucial for regulating the host following viral infection in chickens.
Zhiyuan Wang   +9 more
doaj   +1 more source

Investigation of the role of polysaccharide in the dolomite growth at low temperature by using atomistic simulations [PDF]

open access: yesLangmuir 31.38 (2015): 10435-10442, 2016
Dehydration of water from surface Mg2+ is most likely the rate-limiting step in the dolomite growth at low temperature. Here, we investigate the role of polysaccharide in this step using classical molecular dynamics (MD) calculations. Free energy (potential of mean force, PMF) calculations have been performed for water molecules leaving the first two ...
arxiv  

Hollow‐Structured Nanorobot with Excellent Magnetic Propulsion for Catalytic Pollutant Degradation, Anti‐Bacterial and Biofilm Removal

open access: yesAdvanced Healthcare Materials, EarlyView.
A hollow‐structured Fe3O4@AgAu@PDA‐ZnPc nanosphere has been developed, exhibiting controllable catalytic activity and “photothermal‐photodynamic‐Ag+” coupling antibacterial characteristics. When subjected to a rotating magnetic field, these performances are uniquely enhanced by magnetic propulsion, allowing the nanosphere to function as a magnetic ...
Jing Wang   +7 more
wiley   +1 more source

Structure Design of Polysaccharides by Selective Conversion: Old Hat or Topical?

open access: yesBioResources, 2023
The functionalization pattern in polysaccharide derivatives is an important factor that determines their properties and, thus, their functions in applications.
Andreas Koschella, Thomas Heinze
doaj  

Lycium‐Barbarum Polysaccharide‐Loaded Dual‐Crosslinked Rigid Hydrogel Enhances Bone Healing in Diabetic Bone Defects by Scavenging Reactive Oxygen Species

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel hydrogel (HLBP) incorporating natural polysaccharides from goji berries is developed to enhance diabetic bone defect healing. The hydrogel efficiently scavenges ROS, improves osteogenic differentiation, and promotes in vivo bone regeneration. This strategy offers a biocompatible and localized approach, overcoming the challenges of traditional ...
Wenjie Zhong   +9 more
wiley   +1 more source

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