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Protective efficacy of pneumococcal polysaccharide vaccines.
JAMA: The Journal of the American Medical Association, 1977Clinical studies of 6- and 12-valent pneumococcal capsular polysaccharide vaccines were carried out in controlled studies among novice gold miners in South Africa.
P. Smit +4 more
semanticscholar +4 more sources
Bacterial Polysaccharide Vaccines
, 2011Capsulated bacteria, Gram-positive or Gram-negative, cause a variety of infections in man. Prominent among them are streptococci of Lancefield’s groups A, B, and C, staphylococci, meningococci, Haemophilus influenzae type b, klebsiellas, Escherichia coli, and Salmonella typhi, to name but some.
R. Austrian
semanticscholar +3 more sources
Polysaccharides as vaccine adjuvants
Vaccine, 2018Adjuvant is a substance added to vaccine to improve the immunogenicity of antigens, and it can induce stronger immune responses and reduce the dosage and production cost of vaccine in populations responding poorly to vaccination. Adjuvants in development or in use mainly include aluminum salts, oil emulsions, saponins, immune-stimulating complexes ...
Xiaohua Wang +5 more
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CONJUGATED POLYSACCHARIDE VACCINES
Infectious Disease Clinics of North America, 1999The joining of polysaccharide antigens to various proteins can result in increased immunogenicity of vaccines composed of such antigens. This article discusses conjugated polysaccharide vaccines for Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitis.
Edward K. Chapnick, Hussain Ahmad
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Expert Review of Vaccines, 2018
Introduction: Vaccination against group B Streptococcus (GBS) during pregnancy could provide protection against disease in the mother, fetus, and newborn.
Sonwabile Dzanibe, S. Madhi
semanticscholar +1 more source
Introduction: Vaccination against group B Streptococcus (GBS) during pregnancy could provide protection against disease in the mother, fetus, and newborn.
Sonwabile Dzanibe, S. Madhi
semanticscholar +1 more source
Polysaccharide Conjugate Typhoid Vaccine
New England Journal of Medicine, 2001There is a growing appreciation of the huge health threat posed by increasingly resistant infectious diseases, especially in tropical areas of the developing world.
Richard L. Guerrant, Margaret Kosek
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C-POLYSACCHARIDE IN A PNEUMOCOCCAL VACCINE
Acta Pathologica Microbiologica Scandinavica Series C: Immunology, 2009The 14-valent pneumococcal vaccine, Pneumovax, was found to contain approximately 25o micrograms per ml of the cell-wall antigen, C-polysaccharide (C-Ps), in addition to 100 micrograms per ml of each of the 14 capsular polysaccharides. Rabbit anti-C-Ps antiserum recognized four components of this C-Ps with different antigenic determinants ...
Jøgen Henrichsen +1 more
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Efficacy of Pneumococcal Polysaccharide Vaccines [PDF]
Clinical Infectious Diseases, 1981 due to pneumococcal infection. Estimates based on data obtained in this country after licensure of the vaccine suggest that the efficacy in certain groups may be low:
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Vaccines Against Polysaccharide Antigens
Current Drug Target -Infectious Disorders, 2001Encapsulated bacteria such as Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae serogroup B (Hib) are a major cause of disease worldwide. Vaccine development against these organisms has targeted their capsular polysaccharides (CPS), as anti-capsular antibodies often protect against disease.
M. A. Westerink, Gregory B. Lesinski
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Journal of Infectious Diseases, 1977
During an epidemic caused by group A Neisseria meningitidis, 98,272 children (three months to five years of age) were vaccinated in three provinces of Finland. Meningococcal group A and Haemophilus influenzae type b polysaccharide vaccines were used in a
P. Mäkelä +7 more
semanticscholar +1 more source
During an epidemic caused by group A Neisseria meningitidis, 98,272 children (three months to five years of age) were vaccinated in three provinces of Finland. Meningococcal group A and Haemophilus influenzae type b polysaccharide vaccines were used in a
P. Mäkelä +7 more
semanticscholar +1 more source