Results 51 to 60 of about 75,365 (303)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Carcass traits and meat fatty acid composition of Barbarine lambs reared on rangelands or indoors on hay and concentrate

open access: yesAnimal, 2015
The objective of this study was to compare carcass and meat quality between Barbarine lambs raised on rangelands and those reared indoors. A total of 24 weaned male lambs (23.2 kg) were allotted into two groups.
L. Majdoub-Mathlouthi   +2 more
doaj   +1 more source

Milk Fat with Increased Polyunsaturated Fatty Acids

open access: yesJournal of Dairy Science, 1972
Abstract Milk fat with increased polyunsaturated fatty acids was produced by feeding cows a diet containing a formaldehyde-treated safflower oil-casein particle. This treatment protected the linoleic acid of the safflower oil from hydrogenation in the rumen, and the linoleic acid content of the milk increased from 3% to 35% of the total fatty acids ...
R D, Plowman   +8 more
openaire   +2 more sources

Polyunsaturated fatty acids in the pathogenesis and treatment of multiple sclerosis [PDF]

open access: yes, 2007
Epidemiological, biochemical, animal model and clinical trial data described in this overview strongly suggest that polyunsaturated fatty acids, particularly n-6 fatty acids, have a role in the pathogenesis and treatment of multiple sclerosis (MS).
Copeland   +16 more
core   +2 more sources

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

open access: yesAdvanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu   +16 more
wiley   +1 more source

Dietary Lipids and Cancer

open access: yesLibyan Journal of Medicine, 2007
For many years, epidemiological studies continued to suggest that high fat diets are linked to an increased incidence of certain cancers. However, whether the oncogenic properties of fat are associated with their quantity rather than the quality has ...
Rgia A Othman
doaj  

α-Tocopherol protects against diet induced atherosclerosis in New Zealand white rabbits

open access: yesJournal of Lipid Research, 2002
In this study, we asked the question “does α-tocopherol supplementation prevent an increase in total plasma cholesterol (TPC) concentration and reduce the deposition of cholesterol in arterial plaques of rabbits fed atherogenic diets?” Isocaloric diets ...
Dawn C. Schwenke   +3 more
doaj   +1 more source

Variation in the apparent faecal digestibility of macronutrients and urinary energy excretion for three diets varying in fat and fibre content-- assessment of the Atwater factors and related energy conversion factors : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Nutritional Science at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2007
Background: Current systems to estimate dietary metabolisable energy (ME), often based on Atwater factors, assume that diet ME can be accurately predicted based on a few chemical components and that the ME of components is constant across foods ...
Zou, Maggie Long
core  

Replacement of dietary saturated fatty acids by trans fatty acids lowers serum HDL cholesterol and impairs endothelial function in healthy men and women [PDF]

open access: yes, 2001
We tested whether trans fatty acids and saturated fatty acids had different effects on flow-mediated vasodilation (FMD), a risk marker of coronary heart disease (CHD). Consumption of trans fatty acids is related to increased risk of CHD, probably through
Bots, M.L., Katan, M.B., Roos, N.M., de
core   +2 more sources

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo   +14 more
wiley   +1 more source

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