Results 71 to 80 of about 43,140 (225)

Teplizumab in Stage 2 Type 1 Diabetes: Clinical Practice Experience on Feasibility in 3 Adult Patients

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To describe the first Italian experience with teplizumab administered under a compassionate use programme for adults with Stage 2 type 1 diabetes (T1D), and to evaluate its feasibility, safety and early metabolic outcomes in a real‐life clinical setting outside formal clinical trials.
V. Guarnotta, F. Pantò, E. Vigneri, G. Piombo, M. I. Mineo, L. Tomasello, G. Arnaldi   +6 more
wiley   +1 more source

Decreased nitric oxide production is a novel therapeutic target for salt-induced nocturnal polyuria in aging

Scientific Reports
Nocturnal polyuria is a major cause of nocturia, which affects quality of life. Aging-related decreases in nitric oxide production have been reported to contribute to salt-induced nocturnal polyuria.
Takahiro Imanaka, Kentaro Takezawa, Yuma Kujime, Hiroaki Kitakaze, Go Tsujimura, Sohei Kuribayashi, Yosuke Sekii, Norichika Ueda, Shinichiro Fukuhara, Hiroshi Kiuchi, Hiromitsu Negoro, Norio Nonomura   +11 more
doaj   +1 more source

Insipidary syndrome in children and adolescents (part 1)

Лечащий Врач, 2021
The review article presents current data on water-electrolyte balance in healthy and pathological state. The diseases and conditions which occur in insipidary syndrome are described.
V. V. Smirnov, L. I. Bikbaeva
doaj  

Restored vision in a young dog following corticosteroid treatment of presumptive hypophysitis [PDF]

, 2016
Background: Hypophysitis is an umbrella term for a group of disorders involving inflammation of the pituitary gland. A rare occurrence in humans, hypophysitis can produce a range of clinical signs including (but not limited to) visual deficits and ...
Liuti, Tiziana, Marioni-Henry, Katia, Rzechorzek, Nina Marie, Stalin, Catherine   +3 more
core   +2 more sources

MiR‐210‐3p is upregulated in diabetic peripheral neuropathy and may be involved in the progression of the disease by targeting brain‐derived neurotrophic factor

Journal of Diabetes Investigation, EarlyView.
Elevated miR‐210‐3p expression was diagnostic for diabetic peripheral neuropathy (DPN) and served as an independent risk factor for DPN. miR‐210‐3p functioned by negatively regulating BDNF, and its inhibitor reversed hyperglycemia‐induced Schwann cell dysfunction, whereas BDNF knockdown eliminated this protective effect.
Yafei Zhao, Liu Wang, Dongcai Feng
wiley   +1 more source

Insipidary syndrome in children and adolescents (part 3)

Лечащий Врач, 2021
The review article presents current data on water-electrolyte balance in healthy and pathological state. The diseases and conditions which occur in insipidary syndrome are described.
V. V. Smirnov, L. I. Bikbaeva
doaj  

Genetic Deletion of P2Y2 Receptor Offers Long-Term (5 Months) Protection Against Lithium-Induced Polyuria, Natriuresis, Kaliuresis, and Collecting Duct Remodeling and Cell Proliferation

Frontiers in Physiology, 2018
Chronic lithium administration for the treatment of bipolar disorder leads to nephrogenic diabetes insipidus (NDI), characterized by polyuria, natriuresis, kaliuresis, and collecting duct remodeling and cell proliferation among other features. Previously,
Yue Zhang, Yue Zhang, Yue Zhang, Anne Riquier-Brison, Anne Riquier-Brison, Tao Liu, Tao Liu, Yufeng Huang, Noel G. Carlson, Noel G. Carlson, Noel G. Carlson, János Peti-Peterdi, János Peti-Peterdi, Bellamkonda K. Kishore, Bellamkonda K. Kishore, Bellamkonda K. Kishore, Bellamkonda K. Kishore   +16 more
doaj   +1 more source

Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct [PDF]

, 1997
We tested whether severe congestive heart failure (CHF), a condition associated with excess free-water retention, is accompanied by altered regulation of the vasopressin-regulated water channel, aquaporin-2 (AQP2), in the renal collecting duct.
Andersen, D., Ecelbarger, C., Frøkiær, J., Jonassen, T., Knepper, M.A., Marples, D., Nielsen, S., Peterson, J.S., Terris, J.   +8 more
core   +2 more sources

Fulminant type 1 diabetes with high‐titer anti‐glutamic acid decarboxylase antibodies: Likely rapid progression from stage 2 to 3

Journal of Diabetes Investigation, EarlyView.
Abstract A 61‐year‐old man visited our hospital with a sudden onset of polydipsia and polyuria occurring 5 days prior, accompanied by a 5‐kg weight loss. A month prior, his glycated hemoglobin level was 6.2%. Precisely 8 days before the first visit, he had a fever, and hyperglycemic symptoms began shortly thereafter.
Megumi Sato, Junnosuke Miura, Hikaru Oyatsu, Yuka Yoshida, Shota Mochizuki, Michio Otsuki, Tomoko Nakagami   +6 more
wiley   +1 more source

Serum CTRP3 and CysC correlate with glucose, lipid, and bone metabolism in elderly patients with type 2 diabetes mellitus complicated with osteoporosis

Journal of Diabetes Investigation, EarlyView.
Serum levels of CTRP3 and CysC in elderly patients with T2DM and OP are closely associated with glucose‐lipid metabolism, bone mineral density, and bone metabolism markers. Combined detection of these two markers can assist in distinguishing OP in elderly patients with T2DM.
Yi‐Peng Wang, Yong Wang, Tao Chen, Gang Chen, Ze‐Yu Yang   +4 more
wiley   +1 more source