Results 191 to 200 of about 137,660 (279)

Ascites circRNA ASCOR Drives Platinum Resistance of High‐Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation

Advanced Science, EarlyView.
High‐grade serous ovarian carcinoma (HGSOC) is plagued by platinum resistance, with malignant ascites closely linked to poor outcomes. Here, we identify ASCOR, a circRNA enriched in ascites small extracellular vesicles (sEVs) from platinum‐resistant HGSOC patients, as a predictor of poor survival. ASCOR enhances platinum resistance in vitro and in vivo
Hanyuan Liu, Chenchen Zhu, Xuelin Yao, Yi Liu, Jing Zhu, Yuebo Li, Hanjie Xu, Cheng Peng, Ge Shan, Liang Chen, Ying Zhou   +10 more
wiley   +1 more source

Balsam-Pear-Skin-Like-Structure Polyvinylidene Fluoride/Ethylene-Vinyl Alcohol Fibrous Membrane for Highly Efficient Oil/Water Separation Through One-Step Electrospinning. [PDF]

Polymers (Basel)
Jiang Q, Mo J, Han S, Liu X, Qu B, Xie J, Wang X, Zhao J.   +7 more
europepmc   +1 more source

NK Cell Activation by Platinum Boosts Immunotherapy in HR+/HER2− Breast Cancer

Advanced Science, EarlyView.
Multi‐omics and single‐cell analyses identify activated NK cells as key mediators of anti‐PD‐(L)1 response in HR+/HER2− breast cancer. Platinum chemotherapy enhances NK cell cytotoxicity through NF‐κB–associated signaling, synergizing with immunotherapy and providing a rationale for combination treatment.
Yi‐Yu Chen, Yi‐Fan Zhou, Xuan Qi, Ya‐Xin Zhao, Tong Fu, Xi Jin, Minhong Shen, Yi‐Zhou Jiang, Zhi‐Ming Shao   +8 more
wiley   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source

High-Performance Fluorine-Lean Thin Aromatic Hydrocarbon Membranes Based on Polyvinylidene Fluoride for Hydrogen Fuel Cells. [PDF]

Membranes (Basel)
Nemeth T, Han Z, Gubler L.
europepmc   +1 more source

A convenient, reliable, and fast acoustic pressure field measurement method for magnetic resonance-guided high-intensity focused ultrasound systems with phased array transducers [PDF]

, 2018
Altman, Michael B, Chen, Hong, Gach, H Michael, Hallahan, Dennis E, Kothapalli, Satya V.V.N., Partanen, Ari, Zhu, Lifei   +6 more
core   +1 more source

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

Polyvinylidene fluoride/graphene oxide/polyimide composite high-efficiency PM_2.5 filtration nanofiber membranes. [PDF]

RSC Adv
Chen H, Sun X, Wang Y, Shi L, Liu X, Hu N.   +5 more
europepmc   +1 more source

Ambient Stable Triboelectric Nanogenerator Based on Conductive Filler Modified Silicone Rubber with Gas Barrier Encapsulation for Footstep Energy Conversion

Advanced Science, EarlyView.
A humidity‐tolerant triboelectric nanogenerator is developed using conductive carbon black‐modified silicone rubber and a flame‐retardant gas barrier layer. The device efficiently harvests footstep energy while maintaining stable output under 30–90% RH and over 1 million cycles.
Yi Wei, Yushu Tian, Xiaokang Chen, Junfeng Chu, Junjie Wang, Xiangyu Chen, Wenjie Wu, Liqun Zhang   +7 more
wiley   +1 more source