Results 41 to 50 of about 320,389 (303)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
USING PLANTS FOR GREENING OF TAILING PONDS OF IRON ORE COMBINES OF KRYVYI RIH AREA [PDF]
, 2018 The tailing ponds of the iron ore-dressing combines occupy thousands of hectares in Kryvyi Rih area and create a serious ecologic problem in this region.
Baranets, Mykola +8 more
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Yearly growth and metabolic changes in earthen pond-cultured meagre Argyrosomus regius
Scientia Marina, 2014 Metabolic modifications associated with natural environmental conditions were assessed in the meagre Argyrosomus regius cultured in earthen ponds under natural photoperiod and temperature. Juvenile specimens (90-100 g initial weight) were sampled (plasma,
Luis Vargas-Chacoff +4 more
doaj +1 more source
Milkfish nursery pond and pen culture in the Indo-Pacific region [PDF]
, 1984 In culturing milkfish (Chanos chanos ) to marketable size, the fry (total length = 12-15 mm) are usually reared first in nursery ponds or pens (hapa nets) until they become fingerlings (total length = 2 cm or more).
Baliao, Dan D.
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Large-Scale Assessment of Coastal Aquaculture Ponds with Sentinel-1 Time Series Data
Remote Sensing, 2017 We present an earth observation based approach to detect aquaculture ponds in coastal areas with dense time series of high spatial resolution Sentinel-1 SAR data.
Marco Ottinger +2 more
doaj +1 more source
Choosing the best of both worlds [PDF]
, 2011 The great crested newt (Triturus cristatus) is dependent on two environments for its survival: the aquatic habitat necessary for breeding and development, and the terrestrial habitat required for post-breeding and juvenile activities. For a population to
Gustafson, Daniel
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source