Results 51 to 60 of about 158,682 (286)

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

open access: yesAdvanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu   +5 more
wiley   +1 more source

Acetylcholinesterase activity in the pons and medulla oblongata of rats after chronic electroconvulsive shock

open access: yesBrazilian Journal of Medical and Biological Research, 1997
An imbalance between cholinergic and noradrenergic neurotransmission has been proposed for the etiology of affective disorders. According to this hypothesis, depression would be the result of enhanced cholinergic and reduced noradrenergic ...
R. Camarini, M.A.C. Benedito
doaj   +1 more source

Computational and Data‐Driven Strategies for Lignocellulosic Biomass Valorization: From Multiscale Modeling to Digitalized Biorefinery Design

open access: yesAdvanced Science, EarlyView.
This Review critically connects structural recalcitrance, molecular modeling, solvent and catalyst design, pyrolysis, machine learning, reactor simulation, and FAIR digital infrastructure. Emphasis is placed on experimentally validated information transfer across scales, uncertainty and applicability domains, and the recycle, durability, techno ...
Abdullahi Bello Umar   +9 more
wiley   +1 more source

Diffusion Tensor Tractography of the Brainstem Pyramidal Tract: A Study on the Optimal Reduction Factor in Parallel Imaging

open access: yes대한영상의학회지, 2016
Purpose Parallel imaging mitigates susceptibility artifacts that can adversely affect diffusion tensor tractography (DTT) of the pons depending on the reduction (R) factor. We aimed to find the optimal R factor for DTT of the pons that would allow us to
Yun Jung Bae   +4 more
doaj   +1 more source

Les éléments de la langue toscane

open access: yes
beschrieben durch Mr. Franz Pons ...
Pons, Franz
core   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

open access: yesAdvanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan   +8 more
wiley   +1 more source

Get-it [Material gráfico]: sweet and juicy : E. Pons Valencia-España : R.E. 8344.

open access: yes, 1950
Tit. en la etiqueta: "E. Pons / Valencia - España / sweet and juicy R.E.
Anónimo, (S. XX
core   +3 more sources

Hardware‐Native Gaussian Sampling With Probabilistic Ising Machines for Modern Communication Paradigms

open access: yesAdvanced Science, EarlyView.
Probabilistic Ising machines are introduced as hardware‐native Gaussian samplers for edge communication workloads. Tunable variance and sampling density enable accurate distributions for Falcon‐class post‐quantum signatures and diffusion‐based semantic communication.
Davi Rodrigues   +10 more
wiley   +1 more source

Neurodevelopmental Hypothesis about the Etiology of Autism Spectrum Disorders

open access: yesFrontiers in Human Neuroscience, 2017
Previous models or hypotheses of autism spectral disorder (ASD) failed to take into full consideration the chronological and causal developmental trajectory, leading to the emergence of diverse phenotypes through a complex interaction between individual ...
Toshio Inui   +2 more
doaj   +1 more source

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