Results 61 to 70 of about 306 (181)
Integrated Engineering of CAR‐T Cells for Solid Tumours
Cell Proliferation, EarlyView.Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang +5 more
wiley +1 more source
Leveraging urban greenspaces to bolster regional conservation priorities
Conservation Science and Practice, EarlyView.This article demonstrates that urban greenspaces currently excluded from the San Francisco Bay Area's regional conservation plan offer significant, measurable conservation value. We found these overlooked areas host vital biodiversity and critically improve habitat connectivity, highlighting that incorporating urban greenspaces will be key in meeting ...
Cesar O. Estien +5 more
wiley +1 more source
Reframing Justice in Healthcare AI: An Ubuntu‐Based Approach for Africa
Developing World Bioethics, EarlyView.ABSTRACT There is an ongoing debate on how to balance the benefits and risks of artificial intelligence (AI), especially in healthcare. In resource‐constrained settings, such as Africa, where access to quality care remains a challenge, AI has the potential to improve efficiency, accessibility, and patient outcomes.
Aloysius Ochasi +3 more
wiley +1 more source
Semiparametric isotonic regression modelling and estimation for group testing data. [PDF]
Can J Stat, 2021 Yuan A, Piao J, Ning J, Qin J.
europepmc +1 more source
Diabetic Medicine, EarlyView.Abstract Aims CGM devices report glucose only within fixed limits (typically 40–400 mg/dL; 2.2–22.2 mmol/L), truncating extreme values to a boundary (‘capping’). We characterised prevalence, duration, and consequences of capping in type 1 diabetes trial data.
John F. Mulley
wiley +1 more source
Determination of the 95% effective dose of remimazolam tosylate in anesthesia induction inhibits endotracheal intubation response in senile patients. [PDF]
Front Pharmacol, 2023 Qu L +7 more
europepmc +1 more source
Economica, EarlyView.We examine how changes in task content over time condition occupational wage development. Using survey data from Germany, we document substantial heterogeneity in within‐occupation changes in task content. Combining this evidence with administrative data on individual employment outcomes over a 25‐year period, we find important heterogeneity in wage ...
Ronald Bachmann +3 more
wiley +1 more source
Stable reliability diagrams for probabilistic classifiers. [PDF]
Proc Natl Acad Sci U S A, 2021 Dimitriadis T, Gneiting T, Jordan AI.
europepmc +1 more source
How to Demonstrate Trustworthy Use of AI in Public Services: A Case Study
Information Systems Journal, EarlyView.ABSTRACT Government leaders across the globe are grappling with how to harness and integrate artificial intelligence (AI) to enhance public service delivery and efficiency. Yet, a key challenge faced is how to build and maintain the trust of stakeholders. Trust is critical for the acceptance and sustained adoption of AI technologies, as well as to gain
Natalie Smith +5 more
wiley +1 more source
ESTROGEN RECEPTOR EXPRESSION ON BREAST CANCER PATIENTS' SURVIVAL UNDER SHAPE RESTRICTED COX REGRESSION MODEL. [PDF]
Ann Appl Stat, 2021 Qin J, Deng G, Ning J, Yuan A, Shen Y.
europepmc +1 more source